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Table 3 Health-related quality of life (HRQOL) scores according to physical activity levels among breast cancer survivors with stage I breast cancer

From: The association between physical activity and health-related quality of life among breast cancer survivors

HRQOL Items Physical Activity (MET-hours per week)
All Tertile 1 Tertile 2 Tertile 3 P for trenda
EORTC QLQ-C30, LS means (95% CI)b
Global health status / QoL 93 44.40 (27.04, 72.90) 33.27 (20.51, 53.98) 34.72 (20.75, 58.08) 0.35
Functioning
 Physical Functioning 101 74.97 (67.56, 83.20) 76.85 (69.59, 84.87) 84.62 (76.17, 94.00) 0.01
 Role Functioning 101 79.69 (60.00, 105.84) 71.11 (54.25, 93.20) 88.10 (66.14, 117.35) 0.36
 Emotional Functioning 101 83.73 (57.88, 121.12) 79.85 (56.16, 113.54) 80.11 (55.17, 116.33) 0.83
 Cognitive Functioning 101 77.91 (65.43, 92.78) 77.49 (65.61, 91.52) 67.46 (56.55, 80.48) 0.07
 Social Functioning 101 57.30 (39.62, 82.86) 70.40 (49.53, 100.07) 76.72 (52.85, 111.36) 0.12
Symptom
 Fatigue 101 27.95 (17.23, 45.34) 25.32 (15.97, 40.16) 16.29 (9.99, 26.55) 0.02
 Nausea / Vomiting 101 2.56 (1.15, 5.70) 2.75 (1.28, 5.89) 3.06 (1.37, 6.87) 0.64
 Pain 101 11.16 (4.92, 25.29) 7.64 (3.50, 16.65) 5.92 (2.59, 13.52) 0.12
 Dyspnea 99 5.25 (2.13, 12.96) 3.46 (1.46, 8.21) 4.02 (1.60, 10.13) 0.63
 Insomnia 101 14.61 (6.19, 34.49) 14.90 (6.57, 33.78) 22.14 (9.30, 52.72) 0.29
 Appetite loss 100 1.35 (0.54, 3.38) 2.04 (0.86, 4.84) 1.57 (0.63, 3.91) 0.85
 Constipation 101 3.70 (1.42, 9.67) 6.01 (2.41, 15.02) 8.35 (3.17, 22.04) 0.09
 Diarrhea 101 3.01 (1.36, 6.67) 2.27 (1.06, 4.84) 1.63 (0.73, 3.65) 0.12
 Financial Problems 101 2.82 (1.12, 7.07) 3.20 (1.33, 7.69) 1.92 (0.76, 4.86) 0.33
EORTC QLQ-BR23, LS means (95% CI)b
Functioning
 Body image 101 68.77 (39.53, 119.62) 65.36 (38.56, 110.80) 57.80 (33.04, 101.11) 0.51
 Sexual functioning 94 4.12 (1.54, 11.03) 4.56 (1.80, 11.54) 5.57 (2.12, 14.60) 0.50
 Sexual enjoyment 33 53.86 (7.89, 367.75) 36.75 (7.85, 172.11) 21.84 (3.57, 133.78) 0.25
 Future perspective 101 25.27 (10.25, 62.28) 30.21 (12.79, 71.39) 29.68 (11.93, 73.83) 0.75
Symptom
 Systematic therapy side effects 101 16.48 (10.39, 26.14) 15.77 (10.16, 24.48) 12.99 (8.15, 20.70) 0.27
 Breast symptoms 101 5.94 (3.08, 11.44) 6.82 (3.65, 12.74) 5.27 (2.72, 10.22) 0.63
 Arm symptoms 101 13.47 (7.64, 23.77) 13.75 (8.00, 23.62) 11.58 (6.52, 20.54) 0.55
 Upset by hair loss 69 14.10 (4.83, 41.22) 7.35 (2.41, 22.41) 15.16 (4.30, 53.40) 0.80
  1. MET metabolic equivalent, EORTC QLQ-C30 European organization for research and treatment of cancer quality of life questionnaire core 30, LS least-squares, CI confidence interval, EORTC QLQ-BR23 European organization for research and treatment of cancer quality of life questionnaire Breast cancer module 23
  2. aP for trend was calculated using the median value of each tertile category as a continuous variable
  3. bAdjusted for age (year: continuous), energy intake (kcal/day: continuous), dietary supplement use (yes, no), education level (high school or less, college or more), marital status (married or cohabitated, unmarried or divorced or widowed), time since surgery (6 month – 1 year, 1 year - 5 years, ≥5 years), and center