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Table 2 Total healthcare resource utilization in patients with NVAF treated with dabigatran or warfarin

From: Healthcare utilization and costs for patients initiating Dabigatran or Warfarin

Outcome

Dabigatran

Warfarin

P valueb

N

1110

1110

 

Hospitalization

 Number of patients hospitalized, n (%)

284 (25.6)

332 (29.9)

 

 All cause hospitalizations, n

381

475

 

Mean PPPYa [SD] (95% CI)

0.92 [3.10] (0.74, 1.11)

1.13 [2.90] (0.96, 1.30)

0.0124

  Median PPPYa (25p, 75p)

0.0 (0.0, 1.0)

0.0 (0.0, 1.0)

 

ER visits

 Number of patients with an ER visit, n (%)

309 (27.8)

378 (34.1)

 

 All cause ER visits, n

563

780

 

 Mean PPPYa [SD] (95% CI)

1.32 [4.04] (1.08, 1.56)

1.56 [3.74] (1.34, 1.78)

0.0011

  Median PPPYa (25p, 75p)

0.0 (0.0, 1.0)

0.0 (0.0, 1.6)

 

Physician office visits

 Number of patients with a physician office visit, n (%)

1068 (96.2)

1084 (97.7)

 

 All cause physician office visits (n)

11,571

18,765

 

  Mean PPPYa [SD] (95% CI)

21.43 [17.98] (20.37, 22.49)

29.41 [18.68] (28.31, 30.51)

< 0.0001

  Median PPPYa (25p, 75p)

17.0 (10.2, 27.3)

26.4 (16.5, 39.0)

 

Outpatient visits

 Number of patients with an outpatient visit, n (%)

945 (85.1)

1040 (93.7)

 

 All cause outpatient visits (n)

5563

13,029

 

  Mean PPPYa [SD] (95% CI)

10.86 [15.44] (9.95, 11.77)

22.02 [23.37] (20.64, 23.39)

< 0.0001

  Median PPPYa (25p, 75p)

6.6 (3.0, 12.4)

16.6 (6.7, 29.0)

 
  1. PPPY per-patient-per-year, SD standard deviation; CI confidence interval, p percentile, ER emergency room
  2. aPPPY was calculated at the patient level (number of HCRU divided by follow-up months), and summary statistics were derived from this measure. Patients with no HCRU for a particular place of service or event are included in the calculation of PPPY since they contributed time to the denominator
  3. b P values calculated using a Wilcoxon rank-sum test