Sensitivity of alternative measures of functioning and wellbeing for adults with sickle cell disease: comparison of PROMIS® to ASCQ-Me℠

Table 1 ASCQ-Me fixed and short forms^a, corresponding PROMIS short forms, direction of scoring for each

ASCQ-Me	Higher scores mean	PROMIS^b	Higher scores mean
Emotional impact	Better health	Anxiety; Depression	More suffering
Pain impact	Better health	Pain Interference; Pain Behavior	More suffering
Pain episodes^c	More suffering	Pain Interference; Pain Behavior	More suffering
Sleep impact	Better health	Sleep Disturbance; Sleep-Related Impairment	More suffering
Social functioning impact	Better health	Satisfaction with Social Activities; Satisfaction with Social Roles	Better health
Stiffness impact^d	Better health	Physical Functioning	Better health

^aWe use the term “fixed form” to indicate that these are not adaptive measures because all respondents are presented with the same items in the same sequence. All ASCQ-Me short forms are subsets of items from the corresponding ASCQ-Me item banks. The Pain Episodes items are not short forms because they are not drawn from the ASCQ-Me item banks, but they are fixed forms because the items are presented in a fixed sequence
^bWhen more than one PROMIS measure corresponds to an ASCQ-Me measure, each is separated by a semi-colon
^cThe Pain Episodes measure includes two subscales to assess frequency and severity
^dPROMIS does not have a stiffness measure but stiffness is related to physical ability

ISSN: 1477-7525