HRQoL domains | Improveda (n = 16) | Worseninga (n = 34) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Baseline mean (SD) | Follow-up mean (SD) | ES | SRM | p | Baseline mean (SD) | Follow-up mean (SD) | ES | SRM | p | |
SF-36 | ||||||||||
Physical functioning | 70.00 (25.36) | 78.13 (23.09) | 0.32 | 0.44 | 0.129 | 70.29 (23.39) | 63.97 (20.55) | −0.27 | −0.31 | 0.094 |
Role-physical | 53.13 (46.44) | 56.25 (41.33) | 0.07 | 0.07 | 0.832 | 44.85 (40.26) | 39.71 (37.50) | −0.13 | −0.16 | 0.379 |
Bodily pain | 74.25 (27.23) | 72.19 (24.85) | −0.08 | −0.15 | 0.611 | 73.44 (25.17) | 67.91 (26.22) | −0.22 | −0.26 | 0.061 |
General health* | 51.75 (15.64) | 65.56 (20.03) | 0.88 | 0.65 | 0.017 | 52.41 (20.42) | 48.88 (21.14) | −0.17 | −0.19 | 0.271 |
Mental health | 70.50 (19.09) | 73.00 (17.44) | 0.13 | 0.12 | 0.505 | 71.76 (23.88) | 68.12 (20.62) | −0.15 | −0.17 | 0.155 |
Role-emotional | 60.42 (40.77) | 62.50 (29.50) | 0.05 | 0.05 | 0.888 | 58.82 (42.69) | 50.98 (41.22) | −0.18 | −0.19 | 0.388 |
Social functioning† | 71.09 (29.13) | 80.47 (21.39) | 0.32 | 0.34 | 0.190 | 71.32 (24.72) | 61.76 (31.07) | −0.39 | −0.39 | 0.048 |
Vitality† | 61.88 (20.89) | 61.56 (20.06) | −0.01 | −0.02 | 0.813 | 60.15 (23.73) | 52.35 (20.61) | −0.33 | −0.40 | 0.035 |
Total scores† | 64.13 (22.65) | 68.71 (18.71) | 0.20 | 0.30 | 0.191 | 62.88 (21.54) | 56.71 (19.81) | −0.29 | −0.43 | 0.017 |
PDQ-39 | ||||||||||
Mobility** | 22.66 (24.60) | 14.69 (18.97) | 0.32 | 0.72 | 0.010 | 22.57 (23.82) | 29.2 (24.52) | −0.28 | −0.27 | 0.098 |
ADL | 17.45 (18.77) | 12.76 (16.42) | 0.25 | 0.43 | 0.113 | 15.32 (16.69) | 18.26 (18.46) | −0.18 | −0.16 | 0.211 |
Emotional well-being† | 10.68 (12.73) | 9.64 (16.30) | 0.08 | 0.12 | 0.159 | 18.14 (19.65) | 22.67 (18.55) | −0.23 | −0.26 | 0.035 |
Stigma | 13.28 (18.38) | 7.81 (12.18) | 0.30 | 0.27 | 0.236 | 20.59 (22.64) | 23.53 (22.62) | −0.13 | −0.17 | 0.154 |
Social support†† | 8.59 (16.28) | 7.03 (16.51) | 0.10 | 0.09 | 0.932 | 4.78 (8.59) | 15.07 (21.05) | −1.20 | −0.51 | 0.001 |
Cognitions | 12.89 (14.34) | 16.02 (16.61) | −0.22 | −0.19 | 0.429 | 24.26 (20.46) | 29.41 (15.58) | −0.25 | −0.27 | 0.071 |
Communication | 6.25 (9.86) | 10.94 (13.85) | −0.48 | −0.34 | 0.172 | 11.03 (19.43) | 20.59 (21.73) | −0.49 | −0.55 | 0.003 |
Bodily discomfort† | 21.88 (20.16) | 14.06 (14.82) | 0.39 | 0.47 | 0.078 | 21.57 (20.73) | 27.45 (24.41) | −0.28 | −0.32 | 0.049 |
SI†† | 14.21 (9.52) | 11.62 (11.72) | 0.27 | 0.37 | 0.074 | 17.28 (14.22) | 23.28 (14.58) | −0.42 | −0.55 | 0.004 |