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Table 1 Baseline clinico-demographic parameters and health utility scores in GS-US-337-0113 and GS-US-334-0118

From: Health utilities using SF-6D scores in Japanese patients with chronic hepatitis C treated with sofosbuvir-based regimens in clinical trials

 

LDV/SOF

LDV/SOF + RBV

SOF + RBV

P

All

N

171

170

153

 

494

Age, years

59.7 ± 9.2

59.2 ± 9.5

56.8 ± 10.1

0.0310

58.6 ± 9.7

Male

69 (40.4%)

73 (42.9%)

70 (45.8%)

0.62

212 (42.9%)

HCV genotype 1

171 (100.0%)

170 (100.0%)

0 (0.0%)

<0.0001

341 (69.0%)

HCV genotype 2

0 (0.0%)

0 (0.0%)

153 (100.0%)

153 (31.0%)

Treatment-naïve

83 (48.5%)

83 (48.8%)

90 (58.8%)

0.11

256 (51.8%)

Cirrhosis

41 (24.0%)

35 (20.6%)

17 (11.1%)

0.0097

93 (18.8%)

History of anxiety

8 (4.7%)

4 (2.4%)

3 (2.0%)

0.30

15 (3.0%)

History of depression

3 (1.8%)

7 (4.1%)

5 (3.3%)

0.44

15 (3.0%)

History of insomnia

24 (14.0%)

21 (12.4%)

21 (13.7%)

0.89

66 (13.4%)