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Table 6 Responsiveness of measures over time to self-reported hand and wrist functioning; 4 to 12 months

From: An empirical evaluation of the SF-12, SF-6D, EQ-5D and Michigan Hand Outcome Questionnaire in patients with rheumatoid arthritis of the hand

  n T4 T12 Δ (95% CI) SRM (95% CI) ES (95% CI)
MHQ
 Improved 177 64.79 61.04 -3.75 (-6.19 to -1.31) -0.13 (-2.57 to 2.31) -0.19 (-2.63 to 2.25)
 No change 150 56.97 58.53 1.56 (-1.11 to 4.23) 0.06 (-2.61 to 2.73) 0.09 (-2.58 to 2.76)
 Worsened 113 45.37 46.22 0.85 (-2.12 to 3.82) 0.04 (-18.9 to 19.65) 0.05 (-2.92 to 3.02)
EQ-5D (utility)
 Improved 177 0.69 0.67 -0.02 (-0.05 to 0.01_ -0.06 (-0.09 to -0.03) -0.09 (-0.12 to -0.06)
 No change 150 0.62 0.64 0.02 (-0.02 to 0.06) 0.06 (0.03 to 0.10) 0.091 (0.05 to 0.13)
 Worsened 113 0.48 0.57 0.09 (0.03 to 0.15) 0.22 (0.16 to 0.28) 0.31 (0.25 to 0.37)
EQ-5D (VAS)
 Improved 177 75.78 68.92 -6.86 (-9.25 to -4.47) -0.24 (-2.63 to 2.14) -0.35 (-2.74 to 2.03)
 No change 150 67.46 68.55 1.09 (-1.95 to 4.13) 0.04 (-2.99 to 3.08) 0.06 (-2.98 to 3.10)
 Worsened 113 60.43 58.66 -1.77 (-5.21 to 1.67) -0.06 (-3.49 to 3.75) -0.08 (-3.52 to 3.35)
SF-12 (PCS)
 Improved 177 36.63 34.19 -2.44 (-4.45 to -0.43) -0.12 (-2.13 to 1.88) -0.17 (-2.18 to 1.83)
 No change 150 34.48 35.22 0.74 (-1.04 to 2.52) 0.05 (-1.74 to 1.83) 0.06 (-1.72 to 1.85)
 Worsened 113 30.44 29.64 -0.8 (-2.84 to 1.24) -0.05 (-2.09 to 1.99) -0.07 (-2.11 to 1.97)
SF-12 (MCS)
 Improved 177 48.12 47.16 -0.96 (-3.22 to 1.31) -0.04 (-2.31 to 2.22) -0.17 (-2.17 to 1.84)
 No change 150 49.29 50.81 1.52 (-0.50 to 3.54) 0.09 (-1.93 to 2.11) 0.13 (-1.89 to 2.15)
 Worsened 113 44 44.96 0.96 (-1.69 to 3.61) 0.04 (-2.61 to 2.69) 0.06 (-2.59 to 2.72)
SF-6D
 Improved 177 0.68 0.64 -0.04 (-0.06 to -0.02) -0.15 (-0.17 to -0.13) -0.22 (-0.24 to -0.19)
 No change 150 0.65 0.67 0.02 (0.00 to 0.04) 0.18 (0.09 to 0.13) 0.15 (0.13 to 0.18)
 Worsened 113 0.59 0.6 0.01 (-0.02 to 0.04) 0.05 (0.02 to 0.07) 0.06 (0.04 to 0.09)