Table 7 Mean difference between the two assessments (T2 minus T1) for Treatment group patients, comparing patients without toxicities with patients who experienced toxicities during treatment, in order to assess sensitivity to change

 Urinary

41

−18.49 (22.80)

−0.81

43

−27.64 (19.44)

−1.42

0.051

 Bowel

40

−11.30 (17.15)

−0.66

39

−9.16 (12.16)

−0.75

0.522

 Sexual

48

−13.61 (17.72)

−0.77

44

−30.59 (24.42)

−1.25

<0.001

 Hormonal

36

−6.48 (13.67)

−0.47

41

−5.29 (10.24)

−0.52

0.664

  Function

52

−18.48 (22.57)

−0.82

47

−31.57 (21.21)

−1.49

0.004

  Bother

39

−20.25 (24.54)

−0.83

41

−24.03 (24.01)

−1.00

0.489

  Irritation/obstruction

40

−16.96 (23.39)

−0.73

41

−15.90 (21.00)

−0.76

0.830

  Incontinence

41

−18.13 (29.86)

−0.61

43

−45.67 (31.66)

−1.44

<0.001

  Function

51

−11.03 (17.15)

−0.64

48

−10.79 (15.21)

−0.71

0.941

  Bother

39

−9.20 (17.01)

−0.54

39

−6.01 (15.49)

−0.39

0.389

  Function

47

−21.80 (23.42)

−0.93

44

−38.68 (24.32)

−1.59

0.001

  Bother

41

1.83 (24.34)

0.07

43

−14.10 (37.05)

−0.38

0.022

  Function

49

−5.13 (14.10)

−0.36

46

−7.42 (15.61)

−0.47

0.454

  Bother

38

−6.64 (14.89)

−0.45

41

−4.27 (10.75)

−0.40

0.422