Skip to main content

Table 2 Change in HRQoL in Chinese women with PCOS along with metformin treatment duration

From: Metformin improved health-related quality of life in ethnic Chinese women with polycystic ovary syndrome

WHOQOL-Bref Total
Mean (SD)
Subgroups
Normal weight
Mean (SD)
Overweight
Mean (SD)
Non- hyperandrogenism
Mean (SD)
Hyperandrogenism
Mean (SD)
 Total scores (16–80)
  Visit 1 (baseline) 55.05 ± 6.75 56.51 ± 6.27 53.80 ± 6.97 58.34 ± 6.27 54.14 ± 6.65
  Visit 2 (1st -2nd month of treatment) 56.19 ± 7.38 57.54 ± 7.15 55.05 ± 7.48 60.87 ± 6.98 55.90 ± 7.02
  Visit 3(3rd- 4th month of treatment) 55.25 ± 7.81 57.00 ± 7.53 53.72 ± 7.85 59.91 ± 7.62 54.16 ± 7.52
 Physical domain (4–20)
  Visit 1 14.38 ± 1.78 14.52 ± 1.71 14.26 ± 1.86 15.11 ± 1.64 14.18 ± 1.78
  Visit 2 14.97 ± 1.90 15.03 ± 1.89 14.91 ± 1.93 16.00 ± 1.87 14.68 ± 1.82
  Visit 3 14.78 ± 1.96 14.98 ± 2.12 14.60 ± 1.82 15.79 ± 1.70 14.54 ± 1.95
 Psychological domain (4–20)
  Visit 1 12.64 ± 2.27 13.12 ± 2.04 12.23 ± 2.40 13.46 ± 2.10 12.41 ± 2.29
  Visit 2 12.77 ± 2.37 13.25 ± 2.31 12.35 ± 2.37 14.29 ± 2.27 12.34 ± 2.24
  Visit 3 12.68 ± 2.48 13.36 ± 1.91 12.09 ± 2.78 14.06 ± 2.56 12.35 ± 2.37
 Social domain (4–20)
  Visit 1 14.01 ± 1.85 14.47 ± 1.58 13.63 ± 2.00 14.94 ± 1.48 13.76 ± 1.88
  Visit 2 14.27 ± 2.17 14.82 ± 1.98 13.80 ± 2.23 15.69 ± 1.85 13.88 ± 2.09
  vVisit 3 13.88 ± 2.16 14.41 ± 1.99 13.42 ± 2.23 15.27 ± 2.00 13.55 ± 2.08
 Environment domain (4–20)
  Visit 1 14.02 ± 1.90 14.40 ± 1.91 13.69 ± 1.84 14.83 ± 1.86 13.79 ± 1.86
  Visit 2 14.19 ± 2.01 14.43 ± 1.93 13.99 ± 2.08 14.89 ± 2.06 14.00 ± 1.97
  Visit 3 13.92 ± 2.13 14.26 ± 2.31 13.62 ± 1.95 14.79 ± 1.97 13.71 ± 2.13
 Chi-PCOSQ
 Total scores (6–42)
  Visit 1 (baseline) 24.53 ± 7.61 25.37 ± 7.56 23.82 ± 7.68 27.68 ± 6.50 23.66 ± 7.72
  Visit 2 (1st -2nd month of treatment) 25.41 ± 7.33 26.47 ± 7.40 24.51 ± 7.25 28.31 ± 7.41 24.61 ± 7.17
  Visit 3(3rd- 4th month of treatment) 25.63 ± 7.21 27.37 ± 7.88 24.12 ± 6.32 28.58 ± 7.60 24.94 ± 7.02
 Weight domain (1–7)
  Visit 1 3.25 ± 1.59 3.91 ± 1.58 2.67 ± 1.38 3.69 ± 1.18 3.12 ± 1.68
  Visit 2 3.34 ± 1.61 4.17 ± 1.59 2.63 ± 1.25 3.98 ± 1.38 3.16 ± 1.62
  Visit 3 3.43 ± 1.49 4.20 ± 1.55 2.76 ± 1.08 3.89 ± 1.25 3.32 ± 1.54
 Infertility domain (1–7)
  Visit 1 3.38 ± 1.93 3.27 ± 1.78 3.48 ± 2.07 3.88 ± 2.17 3.25 ± 1.86
  Visit 2 3.59 ± 2.01 3.43 ± 1.84 3.73 ± 2.16 3.75 ± 2.36 3.55 ± 1.93
  Visit 3 3.76 ± 1.91 3.84 ± 1.85 3.70 ± 2.00 4.00 ± 2.18 3.71 ± 1.87
 Menstrual domain (1–7)
  Visit 1 3.67 ± 1.53 3.67 ± 1.48 3.68 ± 1.60 3.55 ± 1.42 3.71 ± 1.57
  Visit 2 3.94 ± 1.45 3.98 ± 1.40 3.92 ± 1.50 3.81 ± 1.35 3.98 ± 1.48
  Visit 3 3.92 ± 1.31 4.10 ± 1.30 3.76 ± 1.31 4.04 ± 1.38 3.89 ± 1.31
 Emotions domain (1–7)
  Visit 1 4.65 ± 1.77 4.72 ± 1.59 4.59 ± 1.97 4.90 ± 1.77 4.58 ± 1.78
  Visit 2 4.84 ± 1.65 4.93 ± 1.53 4.76 ± 1.76 5.13 ± 1.69 4.76 ± 1.64
  Visit 3 4.79 ± 1.71 5.04 ± 1.78 4.47 ± 1.64 5.05 ± 1.86 4.73 ± 1.69
 Body hair domain (1–7)
  Visit 1 5.37 ± 1.60 5.45 ± 1.73 5.30 ± 1.50 6.19 ± 0.99 5.14 ± 1.67
  Visit 2 5.38 ± 1.55 5.61 ± 1.56 5.18 ± 1.53 6.20 ± 1.17 5.15 ± 1.57
  Visit 3 5.31 ± 1.62 5.67 ± 1.65 5.00 ± 1.54 6.02 ± 1.27 5.14 ± 1.65
 Acne & Hair loss domain (1–7)
  Visit 1 4.21 ± 1.63 4.34 ± 1.57 4.10 ± 1.69 5.48 ± 1.16 3.86 ± 1.57
  Visit 2 4.32 ± 1.58 4.35 ± 1.66 4.29 ± 1.53 5.44 ± 1.37 4.01 ± 1.50
  Visit 3 4.41 ± 1.40 4.50 ± 1.60 4.34 ± 1.22 5.58 ± 1.33 4.14 ± 1.28