Table 2 Change in HRQoL in Chinese women with PCOS along with metformin treatment duration
WHOQOL-Bref | Total Mean (SD) | Subgroups | |||
|---|---|---|---|---|---|
Normal weight Mean (SD) | Overweight Mean (SD) | Non- hyperandrogenism Mean (SD) | Hyperandrogenism Mean (SD) | ||
Total scores (16–80) | |||||
Visit 1 (baseline) | 55.05 ± 6.75 | 56.51 ± 6.27 | 53.80 ± 6.97 | 58.34 ± 6.27 | 54.14 ± 6.65 |
Visit 2 (1st -2nd month of treatment) | 56.19 ± 7.38 | 57.54 ± 7.15 | 55.05 ± 7.48 | 60.87 ± 6.98 | 55.90 ± 7.02 |
Visit 3(3rd- 4th month of treatment) | 55.25 ± 7.81 | 57.00 ± 7.53 | 53.72 ± 7.85 | 59.91 ± 7.62 | 54.16 ± 7.52 |
Physical domain (4–20) | |||||
Visit 1 | 14.38 ± 1.78 | 14.52 ± 1.71 | 14.26 ± 1.86 | 15.11 ± 1.64 | 14.18 ± 1.78 |
Visit 2 | 14.97 ± 1.90 | 15.03 ± 1.89 | 14.91 ± 1.93 | 16.00 ± 1.87 | 14.68 ± 1.82 |
Visit 3 | 14.78 ± 1.96 | 14.98 ± 2.12 | 14.60 ± 1.82 | 15.79 ± 1.70 | 14.54 ± 1.95 |
Psychological domain (4–20) | |||||
Visit 1 | 12.64 ± 2.27 | 13.12 ± 2.04 | 12.23 ± 2.40 | 13.46 ± 2.10 | 12.41 ± 2.29 |
Visit 2 | 12.77 ± 2.37 | 13.25 ± 2.31 | 12.35 ± 2.37 | 14.29 ± 2.27 | 12.34 ± 2.24 |
Visit 3 | 12.68 ± 2.48 | 13.36 ± 1.91 | 12.09 ± 2.78 | 14.06 ± 2.56 | 12.35 ± 2.37 |
Social domain (4–20) | |||||
Visit 1 | 14.01 ± 1.85 | 14.47 ± 1.58 | 13.63 ± 2.00 | 14.94 ± 1.48 | 13.76 ± 1.88 |
Visit 2 | 14.27 ± 2.17 | 14.82 ± 1.98 | 13.80 ± 2.23 | 15.69 ± 1.85 | 13.88 ± 2.09 |
vVisit 3 | 13.88 ± 2.16 | 14.41 ± 1.99 | 13.42 ± 2.23 | 15.27 ± 2.00 | 13.55 ± 2.08 |
Environment domain (4–20) | |||||
Visit 1 | 14.02 ± 1.90 | 14.40 ± 1.91 | 13.69 ± 1.84 | 14.83 ± 1.86 | 13.79 ± 1.86 |
Visit 2 | 14.19 ± 2.01 | 14.43 ± 1.93 | 13.99 ± 2.08 | 14.89 ± 2.06 | 14.00 ± 1.97 |
Visit 3 | 13.92 ± 2.13 | 14.26 ± 2.31 | 13.62 ± 1.95 | 14.79 ± 1.97 | 13.71 ± 2.13 |
Chi-PCOSQ | |||||
Total scores (6–42) | |||||
Visit 1 (baseline) | 24.53 ± 7.61 | 25.37 ± 7.56 | 23.82 ± 7.68 | 27.68 ± 6.50 | 23.66 ± 7.72 |
Visit 2 (1st -2nd month of treatment) | 25.41 ± 7.33 | 26.47 ± 7.40 | 24.51 ± 7.25 | 28.31 ± 7.41 | 24.61 ± 7.17 |
Visit 3(3rd- 4th month of treatment) | 25.63 ± 7.21 | 27.37 ± 7.88 | 24.12 ± 6.32 | 28.58 ± 7.60 | 24.94 ± 7.02 |
Weight domain (1–7) | |||||
Visit 1 | 3.25 ± 1.59 | 3.91 ± 1.58 | 2.67 ± 1.38 | 3.69 ± 1.18 | 3.12 ± 1.68 |
Visit 2 | 3.34 ± 1.61 | 4.17 ± 1.59 | 2.63 ± 1.25 | 3.98 ± 1.38 | 3.16 ± 1.62 |
Visit 3 | 3.43 ± 1.49 | 4.20 ± 1.55 | 2.76 ± 1.08 | 3.89 ± 1.25 | 3.32 ± 1.54 |
Infertility domain (1–7) | |||||
Visit 1 | 3.38 ± 1.93 | 3.27 ± 1.78 | 3.48 ± 2.07 | 3.88 ± 2.17 | 3.25 ± 1.86 |
Visit 2 | 3.59 ± 2.01 | 3.43 ± 1.84 | 3.73 ± 2.16 | 3.75 ± 2.36 | 3.55 ± 1.93 |
Visit 3 | 3.76 ± 1.91 | 3.84 ± 1.85 | 3.70 ± 2.00 | 4.00 ± 2.18 | 3.71 ± 1.87 |
Menstrual domain (1–7) | |||||
Visit 1 | 3.67 ± 1.53 | 3.67 ± 1.48 | 3.68 ± 1.60 | 3.55 ± 1.42 | 3.71 ± 1.57 |
Visit 2 | 3.94 ± 1.45 | 3.98 ± 1.40 | 3.92 ± 1.50 | 3.81 ± 1.35 | 3.98 ± 1.48 |
Visit 3 | 3.92 ± 1.31 | 4.10 ± 1.30 | 3.76 ± 1.31 | 4.04 ± 1.38 | 3.89 ± 1.31 |
Emotions domain (1–7) | |||||
Visit 1 | 4.65 ± 1.77 | 4.72 ± 1.59 | 4.59 ± 1.97 | 4.90 ± 1.77 | 4.58 ± 1.78 |
Visit 2 | 4.84 ± 1.65 | 4.93 ± 1.53 | 4.76 ± 1.76 | 5.13 ± 1.69 | 4.76 ± 1.64 |
Visit 3 | 4.79 ± 1.71 | 5.04 ± 1.78 | 4.47 ± 1.64 | 5.05 ± 1.86 | 4.73 ± 1.69 |
Body hair domain (1–7) | |||||
Visit 1 | 5.37 ± 1.60 | 5.45 ± 1.73 | 5.30 ± 1.50 | 6.19 ± 0.99 | 5.14 ± 1.67 |
Visit 2 | 5.38 ± 1.55 | 5.61 ± 1.56 | 5.18 ± 1.53 | 6.20 ± 1.17 | 5.15 ± 1.57 |
Visit 3 | 5.31 ± 1.62 | 5.67 ± 1.65 | 5.00 ± 1.54 | 6.02 ± 1.27 | 5.14 ± 1.65 |
Acne & Hair loss domain (1–7) | |||||
Visit 1 | 4.21 ± 1.63 | 4.34 ± 1.57 | 4.10 ± 1.69 | 5.48 ± 1.16 | 3.86 ± 1.57 |
Visit 2 | 4.32 ± 1.58 | 4.35 ± 1.66 | 4.29 ± 1.53 | 5.44 ± 1.37 | 4.01 ± 1.50 |
Visit 3 | 4.41 ± 1.40 | 4.50 ± 1.60 | 4.34 ± 1.22 | 5.58 ± 1.33 | 4.14 ± 1.28 |