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Table 3 Discrimination between severity groups of oral cancer

From: A comparison of health state utility values associated with oral potentially malignant disorders and oral cancer in Sri Lanka assessed using the EQ-5D-3 L and the EORTC-8D

MAUI Cancer severity Mean (SD) Median Effect size
EQ-5D-3 L
  OPMD 0.78 (0.19) 0.79  
  Stage 1 0.76 (0.17) 0.78 0.025
  Stage 2 0.69 (0.28) 0.77 0.092
  Stage 3 0.57 (0.22) 0.56 0.174
  Stage 4 0.48 (0.46) 0.59 0.158
EORTC-8D
  OPMD 0.84 (0.17) 0.90  
  Stage 1 0.83 (0.14) 0.85 0.011
  Stage 2 0.73 (0.23) 0.78 0.120
  Stage 3 0.65 (0.21) 0.63 0.109
  Stage 4 0.61 (0.32) 0.72 0.061
  1. Stage 1 -The cancer is less than 2 cm in size, and has not spread to lymph nodes in the area; Stage 2 - The cancer is more than 2 cm in size, but less than 4 cm, and has not spread to lymph nodes in the area; Stage 3 - The cancer is bigger than 4 cm but has not spread to any lymph nodes or other parts of the body; Stage 4- The cancer is either greater than 4 cm in largest diameter or is of any size but has metastasised to regional lymph nodes; SD = standard deviation; Kruskal-Wallis test was used to determine the significance of difference between severity classes, p < 0.05; Wilcoxon matched paired rank test was used to test the significance between utility scores for each severity class, p < 0.05; MAUI = multi attribute utility instrument