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Table 4 Relationship between percent reduction from baseline in VAS and improvement on the PGIC

From: Relationship between pain relief, reduction in pain-associated sleep interference, and overall impression of improvement in patients with postherpetic neuralgia treated with extended-release gabapentin

 

≥30 % reduction in VAS

<30 % reduction in VAS

Difference

p-value

(n = 285)

(n = 240)

% (95 % CI)

“Much” or “Very Much” improved on PGIC, n (%)

200 (70.2)

43 (17.9)

52.26 (45.06, 59.45)

<0.0001

Not improved on PGICa, n (%)

85 (29.8)

197 (82.1)

−52.26 (−59.45, −45.06)

<0.0001

Difference, % (95 % CI)

40.35 (32.84, 47.86)

−64.17 (−71.03, −57.31)

n/a

n/a

p-value

<0.0001

<0.0001

n/a

n/a

  1. aIncludes patients from other PGIC categories: Minimally Improved, No Change, Minimally Worse, Much Worse, Very Much Worse; n/a, not applicable