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Table 4 Relationship between percent reduction from baseline in VAS and improvement on the PGIC

From: Relationship between pain relief, reduction in pain-associated sleep interference, and overall impression of improvement in patients with postherpetic neuralgia treated with extended-release gabapentin

  ≥30 % reduction in VAS <30 % reduction in VAS Difference p-value
(n = 285) (n = 240) % (95 % CI)
“Much” or “Very Much” improved on PGIC, n (%) 200 (70.2) 43 (17.9) 52.26 (45.06, 59.45) <0.0001
Not improved on PGICa, n (%) 85 (29.8) 197 (82.1) −52.26 (−59.45, −45.06) <0.0001
Difference, % (95 % CI) 40.35 (32.84, 47.86) −64.17 (−71.03, −57.31) n/a n/a
p-value <0.0001 <0.0001 n/a n/a
  1. aIncludes patients from other PGIC categories: Minimally Improved, No Change, Minimally Worse, Much Worse, Very Much Worse; n/a, not applicable