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Table 2 Testing the mediating effect of sense of coherence (SOC scale scores) in relationship between HRQoL dimensions at baseline (T1 scale scores) and the same dimensions 6 months later (T2 scale scores) in women with breast cancer (n = 162) by three steps of multiple linear regression analysis, Sobel test and Bootstrap

From: Sense of coherence as a mediator of health-related quality of life dimensions in patients with breast cancer: a longitudinal study with prospective design

 

Standardized beta coefficient (b)b

 

Bootstrapped confidence interval (CI)

Mediation chain: IV1 → M2 → DV3

IV→ M

IV→ DV

IV→ DV M4

Sobel test

CI 95 % Lower

CI 95 % Upper

EORTC QLQ-C30 Scales:

QoL-T1 → SOC-T2 → QoL-T2

.27a

.24b

.10

3.26a

.45

.93

EF-T1 → SOC-T2 → EF-T2

.23b

.27b

.16c

2.72b

.11

.27

CF-T1 → SOC-T2 → CF-T2

.23b

.16c

.09

2.36c

.19

.65

SF-T1 → SOC-T2 → SF-T2

.18c

.19c

.13

2.04c

.36

.83

FA-T1 → SOC-T2 → FA-T2

-.17c

.25b

.19b

2.03c

-.93

-.42

FI-T1 → SOC-T2 → FI-T2

-.17c

.32a

.29a

1.63

-.88

-.10

Health Index

HI-T1 → SOC-T2 → HI-T2

.32a

.48a

.34a

3.62a

.11

.18

SF-12v2 Scales:

MCS-T1 → SOC-T2 → MCS-T2

.37a

.42a

.21b

4.36a

.37

.60

  1. a p < 0.001, b p < 0.01, c p < 0.05
  2. bThe variables of age, educational level and cancer stage were controlled for in all multiple linear regression analyses
  3. 1IV, independent variable (HRQoL dimensions at T1)
  4. 2M, mediator (SOC scale scores at T2)
  5. 3DV, dependent variable (HRQoL dimensions at T2)
  6. 4Relationship between IV and DV after controlling for the mediator