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Table 4 Odds ratio (95 % CI) and area under the curve (AUC) for poor physical and mental HRQoL according to different definitions of metabolic syndrome

From: Which insulin resistance-based definition of metabolic syndrome has superior diagnostic value in detection of poor health-related quality of life? Cross-sectional findings from Tehran Lipid and Glucose Study

 

WHO

EGIR

AACE

 

Physical component summary (PCS)

Men

   

Number of individuals with MetS and poor HRQoL(%)

37 (34.6)

16 (32.7)

24 (38.7)

Adjusted Odds ratio (95 % CI)

   

 Model 1

1.89 (1.00–3.57)**

2.04 (0.83–5.03)

1.75 (0.82–3.71)

 Model 2

1.83 (0.96–3.49)*

2.05 (0.83–5.07)

1.72 (0.77–3.84)

 Model 3

1.72 (0.88–3.35)

1.80 (0.69–4.69)

1.95 (0.84–4.53)

 AUC

0.64 (0.56–0.73)

0.66 (0.56–0.75)

0.66 (0.56–0.76)

Women

   

Number of individuals with MetS and poor HRQoL

70 (35.9)

30 (30)

46 (39.3)

Adjusted Odds ratio (95 % CI)

   

 Model 1

1.51 (0.97–2.37)*

1.21 (0.67–2.19)

1.56 (0.92–2.64)

 Model 2

1.08 (0.67–1.75)

1.06 (0.57–1.96)

0.98 (0.55–1.76)

 Model 3

0.96 (0.57–1.60)

0.93 (0.48–1.81)

1.01 (0.55–1.85)

 AUC

0.73 (0.68–0.79)

0.74 (0.67–0.80)

0.73 (0.67–0.79)

 

Mental component summary (MCS)

Men

   

Number of individuals with MetS and poor HRQoL(%)

33 (30.8)

17 (34.7)

18 (29)

Adjusted Odds ratio (95 % CI)

   

 Model 1

0.92 (0.49–1.73)

1.16 (0.52–2.59)

0.74 (0.35–1.58)

 Model 2

0.95 (0.50–1.80)

1.17 (0.52–2.62)

0.80 (0.36–1.81)

 Model 3

0.75 (0.37–1.49)

0.93 (0.38–2.23)

0.97 (0.41–2.28)

 AUC

0.63 (0.54–0.71)

0.65 (0.55–0.75)

0.65 (0.55–0.74)

Women

   

Number of individuals with MetS and poor HRQoL(%)

71 (36.4)

36 (36)

43 (36.8)

Adjusted Odds ratio (95 % CI)

   

 Model 1

1.14 (0.73–1.77)

1.15 (0.66–1.99)

1.25 (0.74–2.12)

 Model 2

1.00 (0.63–1.58)

1.07 (0.61–1.88)

1.01 (0.57–1.77)

 Model 3

0.89 (0.55–1.45)

0.97 (0.54–1.74)

1.00 (0.56–1.79)

 AUC

0.65 (0.59–0.71)

0.66 (0.59–0.73)

0.65 (0.59–0.72)

  1. WHO, World Health Organization; EGIR, European Group for the study of Insulin Resistance; AACE, American Association of Clinical Endocrinology; HRQoL, Health related quality of life
  2. Model 1: Unadjusted, Model 2: Adjusted for age, Model 3: Adjusted for age, smoking (only in men) (Ref: Never or ex-smoking), education (Ref: Above high school education), marital status (Ref: Married) and menopause (Ref: reproductive age)
  3. * 0.05 ≤ p ≤ 0.07 for poor health-related quality of life
  4. ** P < 0.05 for poor health-related quality of life