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Table 3 Differences in health-related quality of life by socio-demographic and clinical characteristics (N = 629)

From: Health-related quality of life in patients with sickle cell disease in Saudi Arabia

   Emotional well being Social functioning Pain General health
   Mean SD P Mean SD P Mean SD P Mean SD P
Gender Female 60.1 19.7 0.241 60.6 25.7 0.510 49.0 28.5 0.268 47.8 15.7 0.876
Male 58.2 19.1   59.2 24.0   46.5 26.4   48.0 15.6  
Older age No 59.4 19.1 0.711 59.6 24.8 0.280 48.5 27.3 0.257 47.8 15.8 0.980
  Yes 58.6 21.0   62.5 26.1   45.1 29.4   47.9 15.1  
University No 57.3 19.1 0.001* 58.4 24.6 0.003* 46.0 26.9 0.004 46.3 15.2 0.001*
Yes 63.9 19.3   65.4 25.6   53.2 28.5   51.6 16.1  
Married No 60.7 18.8 0.064 61.8 24.8 0.100 50.0 27.7 0.058 48.6 15.3 0.167
Yes 57.7 20.2   58.4 24.8   45.7 27.3   46.8 16.2  
Employed No 58.2 19.5 0.132 58.8 25.2 0.044 46.1 27.7 0.018 47.0 15.2 0.230
Yes 61.0 19.4   63.6 24.4   52.3 27.7   48.8 16.6  
Obese No 59.3 19.4 0.836 61.0 24.7 0.099 48.5 27.9 0.455 47.8 16.1 0.395
Yes 58.6 20.8   54.5 22.1   45.2 24.4   45.5 15.2  
Fever No 63.1 18.5 0.001* 65.9 25.3 0.001* 54.4 28.4 0.001* 51.5 15.3 0.001*
Yes 56.9 19.7   56.2 24.0   43.4 26.2   45.6 15.3  
Skin redness No 61.2 19.7 0.001* 62.6 24.8 0.001* 50.6 28.6 0.001* 50.6 15.3 0.001*
Yes 55.8 18.4   55.0 24.6   42.6 25.4   42.5 15.1  
Swelling No 63.0 19.4 0.001* 65.7 24.7 0.001* 56.4 28.8 0.001* 50.9 15.4 0.001*
Yes 55.1 18.9   53.5 23.9   38.4 23.3   44.5 15.3  
History of blood transfusion No 62.8 18.7 0.045 69.6 24.1 0.001* 59.0 28.2 0.001* 53.2 15.4 0.001*
Yes 58.5 19.5   57.7 24.6   45.8 27.2   46.7 15.5  
Family history of anemia No 63.0 18.3 0.126 66.4 24.7 0.057 55.8 29.0 0.023 48.9 14.6 0.610
Yes 58.8 19.4   59.5 24.8   47.0 27.3   47.7 15.7  
Family support No 56.9 20.6 0.328 60.6 23.8 0.896 53.9 28.4 0.126 51.5 15.3 0.118
Yes 59.8 19.2   60.0 25.2   47.4 27.5   47.6 15.7  
Other Chronic disease No 60.8 19.1 0.001* 61.7 24.5 0.002* 49.1 27.9 0.088 48.4 15.9 0.056
Yes 52.5 19.8   53.0 24.9   43.8 25.1   44.9 14.3  
Regular exercise No 57.5 19.3 0.002* 58.5 24.5 0.031 45.8 27.0 0.011 45.9 15.5 0.001*
Yes 62.8 19.3   63.2 25.4   51.8 28.5   51.0 15.0  
Spleen removed No 59.9 19.3 0.079 60.7 25.0 0.277 48.0 27.5 0.981 48.1 15.6 0.477
Yes 56.2 20.3   57.8 23.9   48.0 28.2   46.9 16.0  
  1. *The factor is significant using Bonferroni correction cut-off at α/n = 0.05/15 = 0.003