Health-related quality of life in patients with sickle cell disease in Saudi Arabia

Ahmed, Anwar E.; Alaskar, Ahmed S.; Al-Suliman, Ahmad M.; Jazieh, Abdul-Rahman; McClish, Donna K.; Al Salamah, Majid; Ali, Yosra Z.; Malhan, Hafiz; Mendoza, May Anne; Gorashi, Abdulrahman O.; El-toum, Mohamed E.; El-toum, Wala E.

doi:10.1186/s12955-015-0380-8

Table 3 Differences in health-related quality of life by socio-demographic and clinical characteristics (N = 629)

		Emotional well being			Social functioning			Pain			General health
		Mean	SD	P	Mean	SD	P	Mean	SD	P	Mean	SD	P
Gender	Female	60.1	19.7	0.241	60.6	25.7	0.510	49.0	28.5	0.268	47.8	15.7	0.876
Gender	Male	58.2	19.1		59.2	24.0		46.5	26.4		48.0	15.6
Older age	No	59.4	19.1	0.711	59.6	24.8	0.280	48.5	27.3	0.257	47.8	15.8	0.980
	Yes	58.6	21.0		62.5	26.1		45.1	29.4		47.9	15.1
University	No	57.3	19.1	0.001*	58.4	24.6	0.003*	46.0	26.9	0.004	46.3	15.2	0.001*
University	Yes	63.9	19.3		65.4	25.6		53.2	28.5		51.6	16.1
Married	No	60.7	18.8	0.064	61.8	24.8	0.100	50.0	27.7	0.058	48.6	15.3	0.167
Married	Yes	57.7	20.2		58.4	24.8		45.7	27.3		46.8	16.2
Employed	No	58.2	19.5	0.132	58.8	25.2	0.044	46.1	27.7	0.018	47.0	15.2	0.230
Employed	Yes	61.0	19.4		63.6	24.4		52.3	27.7		48.8	16.6
Obese	No	59.3	19.4	0.836	61.0	24.7	0.099	48.5	27.9	0.455	47.8	16.1	0.395
Obese	Yes	58.6	20.8		54.5	22.1		45.2	24.4		45.5	15.2
Fever	No	63.1	18.5	0.001*	65.9	25.3	0.001*	54.4	28.4	0.001*	51.5	15.3	0.001*
Fever	Yes	56.9	19.7		56.2	24.0		43.4	26.2		45.6	15.3
Skin redness	No	61.2	19.7	0.001*	62.6	24.8	0.001*	50.6	28.6	0.001*	50.6	15.3	0.001*
Skin redness	Yes	55.8	18.4		55.0	24.6		42.6	25.4		42.5	15.1
Swelling	No	63.0	19.4	0.001*	65.7	24.7	0.001*	56.4	28.8	0.001*	50.9	15.4	0.001*
Swelling	Yes	55.1	18.9		53.5	23.9		38.4	23.3		44.5	15.3
History of blood transfusion	No	62.8	18.7	0.045	69.6	24.1	0.001*	59.0	28.2	0.001*	53.2	15.4	0.001*
History of blood transfusion	Yes	58.5	19.5		57.7	24.6		45.8	27.2		46.7	15.5
Family history of anemia	No	63.0	18.3	0.126	66.4	24.7	0.057	55.8	29.0	0.023	48.9	14.6	0.610
Family history of anemia	Yes	58.8	19.4		59.5	24.8		47.0	27.3		47.7	15.7
Family support	No	56.9	20.6	0.328	60.6	23.8	0.896	53.9	28.4	0.126	51.5	15.3	0.118
Family support	Yes	59.8	19.2		60.0	25.2		47.4	27.5		47.6	15.7
Other Chronic disease	No	60.8	19.1	0.001*	61.7	24.5	0.002*	49.1	27.9	0.088	48.4	15.9	0.056
Other Chronic disease	Yes	52.5	19.8		53.0	24.9		43.8	25.1		44.9	14.3
Regular exercise	No	57.5	19.3	0.002*	58.5	24.5	0.031	45.8	27.0	0.011	45.9	15.5	0.001*
Regular exercise	Yes	62.8	19.3		63.2	25.4		51.8	28.5		51.0	15.0
Spleen removed	No	59.9	19.3	0.079	60.7	25.0	0.277	48.0	27.5	0.981	48.1	15.6	0.477
Spleen removed	Yes	56.2	20.3		57.8	23.9		48.0	28.2		46.9	16.0

*The factor is significant using Bonferroni correction cut-off at α/n = 0.05/15 = 0.003

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