The responsiveness of the EQ-5D and time trade-off scores in schizophrenia, affective disorders, and alcohol addiction

Table 2 Descriptive statistics of the EQ-5D, time trade-off score, WHOQOL-BREF, and GSI at baseline

	Possible range of score (worst-best)	N (schizophrenia/ affective disorders/alcohol addiction)^a	Schizophrenia		Affective disorders		Alcohol addiction		German population norms^b
Instruments	Possible range of score (worst-best)	N (schizophrenia/ affective disorders/alcohol addiction)^a	Mean (SD)	Range	Mean (SD)	Range	Mean (SD)	Range	N	Mean (SD)	Range
EQ-5D index-G	−0.21 – 1.00	106/101/72	.855 (.255)	0.11 – 1.00	.828 (.214)	0.11 – 1.00	.840 (.200)	0.03 – 1.00	3552	.938 (.126)	−0.20 – 1.00
EQ-5D index-UK	−0.59 – 1.00		.735 (.278)	−0.18 – 1.00	.678 (.266)	−0.18 – 1.00	.710 (.230)	−0.15 – 1.00	3552	.908 (.166)	−0.59 – 1.00
EQ VAS score	(0 – 100) /100		.691 (.182)	0.2 – 1.00	.582 (.242)	0 – 1.00	.583 (.212)	0.02 – 1.00	3546	.774 (.193)	0 – 1.00
Time trade off	−1.00 – 1.00		.810 (.310)	−1.00 – 1.00	.700 (.380)	−0.67 – 1.00	.650 (.370)	−0.54 – 1.00	n.a.
WHOQOL-BREF	0 – 100	170/171/161	57.4 (21.0)	0 – 100	44.8 (24.1)	0 – 100	49.4 (21.7)	0 – 100	n.a.
GSI	4 – 0	146/140/147	0.62 (0.52)	2.64 – 0	0.95 (0.71)	3.17 – 0	0.65 (0.60)	3.52 – 0	n.a.

^a Number of observations varied due to missing values; ^b data based on [42]; EQ-5D index-G/UK: German/British EQ-5D index; GSI: global severity index; n.a.: not available for the German population; SD: standard deviation; VAS: visual analogue scale

ISSN: 1477-7525