Health-related quality of life in Parkinson’s disease: a cross-sectional study focusing on non-motor symptoms

Table 4 Spearman’s correlation analysis of clinical variables and PDQ-39 SI scores

Variable	Coefficient	p value
Disease duration	0.30	<0.0001
Clinical subtypes
Tremor dominant	-0.17	0.006
Hypokinetic-rigid dominant	-0.05	0.449
Postural instability and gait disturbance dominant	0.23	<0.0001
HY	0.51	<0.0001
SE-ADL	-0.51	<0.0001
MMSE	-0.25	0.0001
BDI	0.63	<0.0001
Daily dose of levodopa	0.32	<0.0001
Duration of levodopa treatment	0.23	0.0001
Number of comorbidities	0.07	0.5041
MDS-UPDRS Part I – Non-motor experiences of daily living	0.62	<0.0001
MDS-UPDRS Part IA	0.51	<0.0001
MDS-UPDRS Part IB	0.61	<0.0001
Cognitive impairment	0.38	<0.0001
Hallucinacions and psychosis	0.24	0.0001
Depressed mood	0.35	<0.0001
Anxious mood	0.29	<0.0001
Apathy	0.33	<0.0001
ICDs	0.07	0.2490
Nighttime sleep problems	0.29	<0.0001
Daytime sleepiness	0.35	<0.0001
Pain and other sensations	0.38	<0.0001
Urinary problems	0.30	<0.0001
Constipation problems	0.13	0.0281
Lightheadedness on standing	0.34	<0.0001
Fatigue	0.44	<0.0001
MDS-UPDRS Part II – Motor experiences of daily living	0.65	<0.0001
MDS-UPDRS Part III – Motor examination	0.46	<0.0001
MDS-UPDRS Part IV – Motor complications	0.22	0.0003

Abbrevations: PDQ-39, The Parkinson’s Disease Questionnaire; SI, summary index score; HY, Hoehn and Yahr stage; SE-ADL, Schwab and England Activities of Daily Living Scale; MMSE, Mini Mental State Examination; BDI, Beck Depression Inventory; MDS-UPDRS, Movement Disorders Society Unified Parkinson’s Disease Rating Scale; ICDs, Impulse control disorders

ISSN: 1477-7525