Health-related quality of life and tuberculosis: a longitudinal cohort study

Table 4 Mean physical component summary scores reported at each visit by participant group

Visit	Crude estimate	Adjusted estimate ^a	95% Confidence interval adjusted estimate	P-value*
Baseline
Tuberculosis disease	49.5	50.0	49.5 - 50.5	0.001*
Latent tuberculosis infection	50.3	50.6	50.3 - 51.0	0.37
Control^b	50.2	50.7	50.1 - 51.2	-
1 month of treatment
Tuberculosis disease	49.5	49.9	49.4 - 50.5	0.90
Latent tuberculosis infection	50.2	50.5	50.1 - 50.9	0.98
Control	50.2	50.7	50.1 - 51.3	-
2 months of treatment
Tuberculosis disease	49.5	50.0	49.4 - 50.5	0.45
Latent tuberculosis infection	50.3	50.6	50.2 - 51.0	0.95
Control	50.2	50.8	50.3 - 51.3	-
4 months of treatment
Tuberculosis disease	50.0	50.4	49.8 - 51.0	0.89
Latent tuberculosis infection	50.1	50.4	50.0 - 50.8	0.90
Control	50.1	50.8	50.2 - 51.5	-
6 months of treatment
Tuberculosis disease	49.7	50.2	49.7 - 50.7	0.89
Latent tuberculosis infection	50.1	50.5	50.0 - 50.9	0.96
Control	50.1	50.8	50.3 - 51.4	-
9 months of treatment
Tuberculosis disease	49.6	49.9	49.3 - 50.5	0.09
Latent tuberculosis infection	50.3	50.6	50.2 - 51.1	0.90
Control	50.1	51.1	50.5 - 51.8	-
12 months of treatment
Tuberculosis disease	49.6	50.1	49.5 - 50.6	0.04*
Latent tuberculosis infection	50.2	50.6	50.1 - 51.0	0.50
Control	50.0	50.7	50.1 - 51.3	-

^aAdjusted models comparing participants treated for tuberculosis disease to those participants in the untreated control group controlled for age at baseline, sex, other medication exposures at baseline (yes/no) reported in medical charts, and number of individuals residing in participants’ households. Adjusted models comparing participants treated for latent tuberculosis infection to those participants in the untreated control group controlled for age at baseline and sex.
^bControl is a participant screened for tuberculosis who tested negative for tuberculosis and was found not to require treatment.
*Indicates a p-value less than 0.05 meaning a statistically significant difference in mean physical component summary scores reported by the group of treated participants and the participants in the control group in the adjusted model, at the given visit.

ISSN: 1477-7525