|
EQ-5D VAS (Scale 0-100)
|
N
|
1390
|
4713
|
6103
|
|
Baseline
|
75.3 (14.1)
|
75.9 (13.4)
|
75.8 (13.6)
|
|
Week 24
|
82.0 (11.3)
|
82.0 (10.3)
|
82.0 (10.6)
|
|
Change
|
6.7 (15.8)
|
6.1 (14.4)
|
6.2 (14.7)
|
|
P value
|
<0.001
|
<0.001
|
<0.001
|
|
QoL UK (Scale 0-1)
|
N
|
1406
|
4814
|
6220
|
|
Baseline
|
0.851 (0.190)
|
0.882 (0.176)
|
0.875 (0.179)
|
|
Week 24
|
0.886 (0.170)
|
0.896 (0.157)
|
0.893 (0.160)
|
|
Change
|
0.035 (0.228)
|
0.014 (0.218)
|
0.018 (0.221)
|
|
P value
|
<0.001
|
<0.001
|
<0.001
|
|
Mobility dimension
|
N
|
1416
|
4843
|
6259
|
|
No problems with walking (%)
|
Baseline
|
1197 (84.5)
|
4333 (89.5)
|
5530 (88.4)
|
|
Week 24
|
1289 (91.0)
|
4433 (91.5)
|
5722 (91.4)
|
|
P value
|
<0.0001
|
0.0005
|
<0.0001
|
|
Self-care dimension
|
N
|
1415
|
4845
|
6260
|
|
No problems with self-care (%)
|
Baseline
|
1301 (91.9)
|
4475 (92.4)
|
5776 (92.3)
|
|
Week 24
|
1280 (90.5)
|
4483 (92.5)
|
5763 (92.1)
|
|
P value
|
0.1635
|
0.7584
|
0.6655
|
|
Usual activities dimension
|
N
|
1415
|
4841
|
6256
|
|
No problems with performing usual activities (%)
|
Baseline
|
1222 (86.4)
|
4316 (89.2)
|
5538 (88.5)
|
|
Week 24
|
1236 (87.3)
|
4272 (88.2)
|
5508 (88.0)
|
|
P value
|
0.4361
|
0.1578
|
0.4043
|
|
Pain/discomfort dimension
|
N
|
1411
|
4832
|
6243
|
|
No pain or discomfort (%)
|
Baseline
|
1007 (71.4)
|
3820 (79.1)
|
4827 (77.3)
|
|
Week 24
|
1138 (80.7)
|
4031 (83.4)
|
5169 (82.8)
|
|
P value
|
<0.0001
|
<0.0001
|
<0.0001
|
|
Anxiety/depression dimension
|
N
|
1413
|
4837
|
6250
|
|
Not anxious or depressed (%)
|
Baseline
|
1014 (71.8)
|
3624 (74.9)
|
4638 (74.2)
|
|
Week 24
|
1067 (75.5)
|
3749 (77.5)
|
4816 (77.1)
|
|
P value
|
0.0236
|
0.0028
|
0.0002
|
