Table 3 Quality of life in insulin-naïve and insulin-experienced patients, and in the total cohort
Insulin-experienced, N = 1,966 | Insulin-naïve, N = 6,612 | Total cohort, N = 8,578 | ||
|---|---|---|---|---|
EQ-5D VAS (Scale 0-100) | N | 1390 | 4713 | 6103 |
Baseline | 75.3 (14.1) | 75.9 (13.4) | 75.8 (13.6) | |
Week 24 | 82.0 (11.3) | 82.0 (10.3) | 82.0 (10.6) | |
Change | 6.7 (15.8) | 6.1 (14.4) | 6.2 (14.7) | |
P value | <0.001 | <0.001 | <0.001 | |
QoL UK (Scale 0-1) | N | 1406 | 4814 | 6220 |
Baseline | 0.851 (0.190) | 0.882 (0.176) | 0.875 (0.179) | |
Week 24 | 0.886 (0.170) | 0.896 (0.157) | 0.893 (0.160) | |
Change | 0.035 (0.228) | 0.014 (0.218) | 0.018 (0.221) | |
P value | <0.001 | <0.001 | <0.001 | |
Mobility dimension | N | 1416 | 4843 | 6259 |
No problems with walking (%) | Baseline | 1197 (84.5) | 4333 (89.5) | 5530 (88.4) |
Week 24 | 1289 (91.0) | 4433 (91.5) | 5722 (91.4) | |
P value | <0.0001 | 0.0005 | <0.0001 | |
Self-care dimension | N | 1415 | 4845 | 6260 |
No problems with self-care (%) | Baseline | 1301 (91.9) | 4475 (92.4) | 5776 (92.3) |
Week 24 | 1280 (90.5) | 4483 (92.5) | 5763 (92.1) | |
P value | 0.1635 | 0.7584 | 0.6655 | |
Usual activities dimension | N | 1415 | 4841 | 6256 |
No problems with performing usual activities (%) | Baseline | 1222 (86.4) | 4316 (89.2) | 5538 (88.5) |
Week 24 | 1236 (87.3) | 4272 (88.2) | 5508 (88.0) | |
P value | 0.4361 | 0.1578 | 0.4043 | |
Pain/discomfort dimension | N | 1411 | 4832 | 6243 |
No pain or discomfort (%) | Baseline | 1007 (71.4) | 3820 (79.1) | 4827 (77.3) |
Week 24 | 1138 (80.7) | 4031 (83.4) | 5169 (82.8) | |
P value | <0.0001 | <0.0001 | <0.0001 | |
Anxiety/depression dimension | N | 1413 | 4837 | 6250 |
Not anxious or depressed (%) | Baseline | 1014 (71.8) | 3624 (74.9) | 4638 (74.2) |
Week 24 | 1067 (75.5) | 3749 (77.5) | 4816 (77.1) | |
P value | 0.0236 | 0.0028 | 0.0002 |