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Table 5 Health-Related Quality of Life Scores, Overall and by Fibromyalgia Severity Level

From: The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States

   Severity Level  
Scale Overall
(N = 203)
Mild
(N = 21)
Moderate
(N = 49)
Severe
(N = 133)
p-value a
    EQ-5D      
Health State Valuation      < 0.001
n 203 21 49 133  
mean (SD) 0.35 (0.35) 0.76 (0.11) 0.57 (0.21) 0.20 (0.31)  
median (range) 0.52 (0.2- 1.0) 0.76 (0.6 - 1.0) 0.62 (0.0 - 1.0) 0.09 (0.2 - 0.8)  
Overall Health Status
Ratings
     
Current Overall Health      < 0.001
n 203 21 49 133  
mean (SD) 54.9 (21.0) 71.0 (21.5) 62.7 (16.9) 49.4 (20.1)  
median (range) 50.0 (2.0- 100.0) 75.0 (10.0 - 95.0) 65.0 (10.0 - 90.0) 50.0 (2.0 - 100.0)  
Pain-Free Overall Health      0.001
n 202 21 49 132  
mean (SD) 79.3 (20.4) 84.6 (23.9) 84.2 (19.4) 76.6 (19.8)  
median (range) 89.5 (0.0-100.0) 90.0 (10.0 - 100.0) 90.0 (0.0 - 100.0) 80.0 (15.0 - 100.0)  
    Average Pain Intensity      < 0.001
n 202 21 49 132  
mean (SD) 6.3 (2.1) 3.4 (2.0) 5.6 (1.8) 7.0 (1.6)  
median (range) 7.0 (1.0-100.0) 3.0 (1.0 - 7.0) 6.0 (2.0 - 8.0) 7.0 (3.0 - 10.0)  
    FIQ      n/ab
Total Score      
n 203 21 49 133  
mean (SD) 63.2 (19.0) 23.9 (9.5) 49.3 (5.1) 74.5 (9.1)  
median (range) 67.4 (6.0-99.0) 25.9 (6.0 - 38.1) 48.6 (39.9 - 58.9) 73.4 (59.1 - 99.0)  
Physical Impairment      n/ab
n 203 21 49 133  
mean (SD) 5.1 (2.4) 2.4 (2.6) 3.8 (2.1) 6.0 (1.8)  
median (range) 5.0 (0.0-10.0) 1.0 (0.0 - 10.0) 4.0 (0.0 - 10.0) 6.0 (0.0 - 10.0)  
Feel Good      n/ab
n 203 21 49 133  
mean (SD) 7.1 (2.8) 3.1 (2.9) 6.0 (2.3) 8.2 (2.1)  
median (range) 7.1 (0.0-10.0) 2.9 (0.0 - 10.0) 5.7 (0.0 - 10.0) 8.6 (0.0 - 10.0)  
Work Missed      n/ab
n 202 21 49 132  
mean (SD) 4.5 (3.5) 0.9 (2.3) 2.2 (2.3) 5.9 (3.2)  
median (range) 4.3 (0.0-10.0) 0.0 (0.0 - 10.0) 1.4 (0.0 - 10.0) 6.4 (0.0 - 10.0)  
Do Work      n/ab
n 201 21 49 131  
mean (SD) 6.4 (2.7) 1.8 (1.6) 4.7 (1.8) 7.8 (1.6)  
median (range) 7.0 (0.0-10.0) 2.0 (0.0 - 5.0) 5.0 (0.0 - 7.0) 8.0 (4.0 - 10.0)  
Pain      n/ab
n 203 21 49 133  
mean (SD) 7.0 (2.3) 3.0 (1.6) 6.0 (1.8) 7.9 (1.6)  
median (range) 7.0 (1.0-10.0) 3.0 (1.0 - 7.0) 6.0 (2.0 - 9.0) 8.0 (3.0 - 10.0)  
Fatigue/Tired      n/ab
n 203 21 49 133  
mean (SD) 7.9 (2.3) 3.5 (2.0) 6.8 (1.9) 8.9 (1.2)  
median (range) 8.0 (0.0-10.0) 4.0 (0.0 - 7.0) 7.0 (3.0 - 10.0) 9.0 (4.0 - 10.0)  
Rested      n/ab
n 203 21 49 133  
mean (SD) 7.9 (2.3) 4.1 (2.3) 7.1 (1.8) 8.8 (1.6)  
median (range) 8.0 (0.0-10.0) 5.0 (0.0 - 8.0) 7.0 (3.0 - 10.0) 9.0 (2.0 - 10.0)  
Stiffness      n/ab
n 203 21 49 133  
mean (SD) 7.2 (2.4) 3.6 (2.3) 6.4 (1.7) 8.1 (1.9)  
median (range) 8.0 (0.0-10.0) 3.0 (0.0 - 9.0) 6.0 (2.0 - 10.0) 9.0 (2.0 - 10.0)  
Anxiety      n/ab
n 203 21 49 133  
mean (SD) 5.1 (3.2) 1.1 (1.7) 3.2 (2.2) 6.4 (2.8)  
median (range) 5.0 (0.0-10.0) 0.0 (0.0 - 6.0) 3.0 (0.0 - 7.0) 7.0 (0.0 - 10.0)  
Depression      n/ab
n 203 21 49 133  
mean (SD) 5.1 (3.2) 0.6 (0.8) 3.2 (2.4) 6.5 (2.6)  
median (range) 6.0 (0.0-10.0) 0.0 (0.0 - 2.0) 3.0 (0.0 - 9.0) 7.0 (0.0 - 10.0)  
    MOS Sleep      
Sleep Problems Index      < 0.001
n 203 21 49 133  
mean (SD) 57.5 (18.4) 34.4 (13.6) 50.7 (16.9) 63.7 (15.6)  
median (range) 58.3 (13.3-95.6) 33.9 (13.3 - 65.6) 47.8 (20.6 - 88.9) 65.0 (24.4 - 95.6)  
Sleep Disturbance      < 0.001
n 203 21 49 133  
mean (SD) 56.4 (25.3) 31.6 (22.5) 49.0 (22.0) 63.1 (23.8)  
median (range) 56.3 (5.0-100.0) 26.3 (5.0 - 78.8) 42.5 (10.0 - 100.0) 66.3 (5.0 - 100.0)  
Sleep Adequacy      < 0.001
n 203 21 49 133  
mean (SD) 27.9 (23.6) 46.2 (21.8) 34.9 (24.4) 22.5 (21.6)  
median (range) 30.0 (0.0-90.0) 50.0 (0.0 - 80.0) 40.0 (0.0 - 90.0) 20.0 (0.0 - 70.0)  
Sleep Somnolence      < 0.001
n 203 21 49 133  
mean (SD) 52.3 (26.0) 27.6 (17.4) 45.0 (24.0) 58.8 (24.9)  
median (range) 53.3 (0.0-100.0) 20.0 (6.7 - 80.0) 40.0 (0.0 - 100.0) 60.0 (0.0 - 100.0)  
Snoring      0.026
n 201 21 49 131  
mean (SD) 43.3 (36.0) 22.9 (26.3) 46.1 (35.2) 45.5 (36.8)  
median (range) 40.0 (0.0-100.0) 20.0 (0.0 - 100.0) 40.0 (0.0 - 100.0) 40.0 (0.0 - 100.0)  
Shortness of Breath or Headache      0.001
n 202 21 49 132  
mean (SD) 34.3 (30.8) 14.3 (20.1) 29.4 (30.3) 39.2 (30.9)  
median (range) 40.0 (0.0-100.0) 0.0 (0.0 - 60.0) 20.0 (0.0 - 100.0) 40.0 (0.0 - 100.0)  
Sleep Quantity      0.002
n 194 21 49 124  
mean (SD) 6.3 (1.9) 6.8 (1.1) 6.8 (2.0) 6.0 (1.9)  
median (range) 6.0 (1.0-12.0) 7.0 (4.0 - 9.0) 7.0 (1.0 - 11.0) 6.0 (2.0 - 12.0)  
    MAF      
Global Fatigue Index      < 0.001
n 203 21 49 133  
mean (SD) 30.7 (14.2) 16.5 (7.1) 26.3 (12.6) 34.6 (13.8)  
median (range) 35.8 (2.5-50.0) 17.5 (2.5 - 27.2) 29.6 (7.5 - 49.5) 39.4 (7.5 - 50.0)  
    HADS      
Anxiety      < 0.001
n 203 21 49 133  
mean (SD) 10.2 (4.8) 5.5 (3.6) 7.3 (4.2) 12.0 (4.1)  
median (range) 11.0 (0.0-12.0) 4.0 (1.0 - 12.0) 7.0 (0.0 - 16.0) 12.0 (2.0 - 21.0)  
Depression      < 0.001
n 203 21 49 133  
mean (SD) 9.4 (4.4) 3.2 (2.7) 7.2 (2.6) 11.3 (3.8)  
median (range) 9.0 (0.0-21.0) 2.0 (0.0 - 9.0) 7.0 (1.0 - 12.0) 11.0 (2.0 - 21.0)  
  1. a Kruskal-Wallis test.
  2. b P-value not noted due to the association between severity level and FIQ score.
  3. * Source: Subject Questionnaire.