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Table 5 Health-Related Quality of Life Scores, Overall and by Fibromyalgia Severity Level

From: The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States

  

Severity Level

 

Scale

Overall

(N = 203)

Mild

(N = 21)

Moderate

(N = 49)

Severe

(N = 133)

p-value a

    EQ-5D

     

Health State Valuation

    

< 0.001

n

203

21

49

133

 

mean (SD)

0.35 (0.35)

0.76 (0.11)

0.57 (0.21)

0.20 (0.31)

 

median (range)

0.52 (0.2- 1.0)

0.76 (0.6 - 1.0)

0.62 (0.0 - 1.0)

0.09 (0.2 - 0.8)

 

Overall Health Status

Ratings

     

Current Overall Health

    

< 0.001

n

203

21

49

133

 

mean (SD)

54.9 (21.0)

71.0 (21.5)

62.7 (16.9)

49.4 (20.1)

 

median (range)

50.0 (2.0- 100.0)

75.0 (10.0 - 95.0)

65.0 (10.0 - 90.0)

50.0 (2.0 - 100.0)

 

Pain-Free Overall Health

    

0.001

n

202

21

49

132

 

mean (SD)

79.3 (20.4)

84.6 (23.9)

84.2 (19.4)

76.6 (19.8)

 

median (range)

89.5 (0.0-100.0)

90.0 (10.0 - 100.0)

90.0 (0.0 - 100.0)

80.0 (15.0 - 100.0)

 

    Average Pain Intensity

    

< 0.001

n

202

21

49

132

 

mean (SD)

6.3 (2.1)

3.4 (2.0)

5.6 (1.8)

7.0 (1.6)

 

median (range)

7.0 (1.0-100.0)

3.0 (1.0 - 7.0)

6.0 (2.0 - 8.0)

7.0 (3.0 - 10.0)

 

    FIQ

    

n/ab

Total Score

     

n

203

21

49

133

 

mean (SD)

63.2 (19.0)

23.9 (9.5)

49.3 (5.1)

74.5 (9.1)

 

median (range)

67.4 (6.0-99.0)

25.9 (6.0 - 38.1)

48.6 (39.9 - 58.9)

73.4 (59.1 - 99.0)

 

Physical Impairment

    

n/ab

n

203

21

49

133

 

mean (SD)

5.1 (2.4)

2.4 (2.6)

3.8 (2.1)

6.0 (1.8)

 

median (range)

5.0 (0.0-10.0)

1.0 (0.0 - 10.0)

4.0 (0.0 - 10.0)

6.0 (0.0 - 10.0)

 

Feel Good

    

n/ab

n

203

21

49

133

 

mean (SD)

7.1 (2.8)

3.1 (2.9)

6.0 (2.3)

8.2 (2.1)

 

median (range)

7.1 (0.0-10.0)

2.9 (0.0 - 10.0)

5.7 (0.0 - 10.0)

8.6 (0.0 - 10.0)

 

Work Missed

    

n/ab

n

202

21

49

132

 

mean (SD)

4.5 (3.5)

0.9 (2.3)

2.2 (2.3)

5.9 (3.2)

 

median (range)

4.3 (0.0-10.0)

0.0 (0.0 - 10.0)

1.4 (0.0 - 10.0)

6.4 (0.0 - 10.0)

 

Do Work

    

n/ab

n

201

21

49

131

 

mean (SD)

6.4 (2.7)

1.8 (1.6)

4.7 (1.8)

7.8 (1.6)

 

median (range)

7.0 (0.0-10.0)

2.0 (0.0 - 5.0)

5.0 (0.0 - 7.0)

8.0 (4.0 - 10.0)

 

Pain

    

n/ab

n

203

21

49

133

 

mean (SD)

7.0 (2.3)

3.0 (1.6)

6.0 (1.8)

7.9 (1.6)

 

median (range)

7.0 (1.0-10.0)

3.0 (1.0 - 7.0)

6.0 (2.0 - 9.0)

8.0 (3.0 - 10.0)

 

Fatigue/Tired

    

n/ab

n

203

21

49

133

 

mean (SD)

7.9 (2.3)

3.5 (2.0)

6.8 (1.9)

8.9 (1.2)

 

median (range)

8.0 (0.0-10.0)

4.0 (0.0 - 7.0)

7.0 (3.0 - 10.0)

9.0 (4.0 - 10.0)

 

Rested

    

n/ab

n

203

21

49

133

 

mean (SD)

7.9 (2.3)

4.1 (2.3)

7.1 (1.8)

8.8 (1.6)

 

median (range)

8.0 (0.0-10.0)

5.0 (0.0 - 8.0)

7.0 (3.0 - 10.0)

9.0 (2.0 - 10.0)

 

Stiffness

    

n/ab

n

203

21

49

133

 

mean (SD)

7.2 (2.4)

3.6 (2.3)

6.4 (1.7)

8.1 (1.9)

 

median (range)

8.0 (0.0-10.0)

3.0 (0.0 - 9.0)

6.0 (2.0 - 10.0)

9.0 (2.0 - 10.0)

 

Anxiety

    

n/ab

n

203

21

49

133

 

mean (SD)

5.1 (3.2)

1.1 (1.7)

3.2 (2.2)

6.4 (2.8)

 

median (range)

5.0 (0.0-10.0)

0.0 (0.0 - 6.0)

3.0 (0.0 - 7.0)

7.0 (0.0 - 10.0)

 

Depression

    

n/ab

n

203

21

49

133

 

mean (SD)

5.1 (3.2)

0.6 (0.8)

3.2 (2.4)

6.5 (2.6)

 

median (range)

6.0 (0.0-10.0)

0.0 (0.0 - 2.0)

3.0 (0.0 - 9.0)

7.0 (0.0 - 10.0)

 

    MOS Sleep

     

Sleep Problems Index

    

< 0.001

n

203

21

49

133

 

mean (SD)

57.5 (18.4)

34.4 (13.6)

50.7 (16.9)

63.7 (15.6)

 

median (range)

58.3 (13.3-95.6)

33.9 (13.3 - 65.6)

47.8 (20.6 - 88.9)

65.0 (24.4 - 95.6)

 

Sleep Disturbance

    

< 0.001

n

203

21

49

133

 

mean (SD)

56.4 (25.3)

31.6 (22.5)

49.0 (22.0)

63.1 (23.8)

 

median (range)

56.3 (5.0-100.0)

26.3 (5.0 - 78.8)

42.5 (10.0 - 100.0)

66.3 (5.0 - 100.0)

 

Sleep Adequacy

    

< 0.001

n

203

21

49

133

 

mean (SD)

27.9 (23.6)

46.2 (21.8)

34.9 (24.4)

22.5 (21.6)

 

median (range)

30.0 (0.0-90.0)

50.0 (0.0 - 80.0)

40.0 (0.0 - 90.0)

20.0 (0.0 - 70.0)

 

Sleep Somnolence

    

< 0.001

n

203

21

49

133

 

mean (SD)

52.3 (26.0)

27.6 (17.4)

45.0 (24.0)

58.8 (24.9)

 

median (range)

53.3 (0.0-100.0)

20.0 (6.7 - 80.0)

40.0 (0.0 - 100.0)

60.0 (0.0 - 100.0)

 

Snoring

    

0.026

n

201

21

49

131

 

mean (SD)

43.3 (36.0)

22.9 (26.3)

46.1 (35.2)

45.5 (36.8)

 

median (range)

40.0 (0.0-100.0)

20.0 (0.0 - 100.0)

40.0 (0.0 - 100.0)

40.0 (0.0 - 100.0)

 

Shortness of Breath or Headache

    

0.001

n

202

21

49

132

 

mean (SD)

34.3 (30.8)

14.3 (20.1)

29.4 (30.3)

39.2 (30.9)

 

median (range)

40.0 (0.0-100.0)

0.0 (0.0 - 60.0)

20.0 (0.0 - 100.0)

40.0 (0.0 - 100.0)

 

Sleep Quantity

    

0.002

n

194

21

49

124

 

mean (SD)

6.3 (1.9)

6.8 (1.1)

6.8 (2.0)

6.0 (1.9)

 

median (range)

6.0 (1.0-12.0)

7.0 (4.0 - 9.0)

7.0 (1.0 - 11.0)

6.0 (2.0 - 12.0)

 

    MAF

     

Global Fatigue Index

    

< 0.001

n

203

21

49

133

 

mean (SD)

30.7 (14.2)

16.5 (7.1)

26.3 (12.6)

34.6 (13.8)

 

median (range)

35.8 (2.5-50.0)

17.5 (2.5 - 27.2)

29.6 (7.5 - 49.5)

39.4 (7.5 - 50.0)

 

    HADS

     

Anxiety

    

< 0.001

n

203

21

49

133

 

mean (SD)

10.2 (4.8)

5.5 (3.6)

7.3 (4.2)

12.0 (4.1)

 

median (range)

11.0 (0.0-12.0)

4.0 (1.0 - 12.0)

7.0 (0.0 - 16.0)

12.0 (2.0 - 21.0)

 

Depression

    

< 0.001

n

203

21

49

133

 

mean (SD)

9.4 (4.4)

3.2 (2.7)

7.2 (2.6)

11.3 (3.8)

 

median (range)

9.0 (0.0-21.0)

2.0 (0.0 - 9.0)

7.0 (1.0 - 12.0)

11.0 (2.0 - 21.0)

 
  1. a Kruskal-Wallis test.
  2. b P-value not noted due to the association between severity level and FIQ score.
  3. * Source: Subject Questionnaire.
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