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Table 1 Definition of 'Inappropriate therapeutic care' and percentage of patients being managed appropriately by therapeutic aspect evaluated (n = 420 included) [10]

From: Predialysis therapeutic care and health-related quality of life at dialysis onset (The pharmacoepidemiologic AVENIR study)

Therapeutic fields evaluated

Definition of 'Inappropriate therapeutic care'

% of patients being managed appropriately

Hypertension/Proteinuria

Mean BPa >130/80 mmHg without prescription of an antihypertensive agent

72.4

 

Mean proteinuria >0.5 g/dl without prescription of a renin-angiotensin system inhibitor

 

Anemia

Hemoglobin <11 g/dl in two successive readings without prescription of an erythropoiesis-stimulating agent

 
 

Erythropoiesis-stimulating therapy without prescription of iron

56.2

 

Or

 
 

Mean serum ferritin <100 ng/ml without prescription of iron (in patients not given erythropoiesis-stimulating therapy)

 

Bone disease

Mean serum calcium <10.2 mg/dl without prescription of calcium

16.7

 

Mean serum 25-hydroxyvitamin D <30 ng/ml without prescription of ergocalciferol

 
 

Or

 
 

Mean serum 25-hydroxyvitamin D >30 ng/ml and hyperparathyroidism without prescription of alfacalcidol

 

Metabolic acidosis

Mean serum bicarbonates <23 mEq/l without prescription of bicarbonate

60.2

Dyslipidemia

Mean fasting total cholesterol >201 mg/dl or mean triglycerides >150.5 mg/dl without prescription of a lipid-lowering therapy

61.4

  1. a BP, blood pressure.