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Table 1 Definition of 'Inappropriate therapeutic care' and percentage of patients being managed appropriately by therapeutic aspect evaluated (n = 420 included) [10]

From: Predialysis therapeutic care and health-related quality of life at dialysis onset (The pharmacoepidemiologic AVENIR study)

Therapeutic fields evaluated Definition of 'Inappropriate therapeutic care' % of patients being managed appropriately
Hypertension/Proteinuria Mean BPa >130/80 mmHg without prescription of an antihypertensive agent 72.4
  Mean proteinuria >0.5 g/dl without prescription of a renin-angiotensin system inhibitor  
Anemia Hemoglobin <11 g/dl in two successive readings without prescription of an erythropoiesis-stimulating agent  
  Erythropoiesis-stimulating therapy without prescription of iron 56.2
  Or  
  Mean serum ferritin <100 ng/ml without prescription of iron (in patients not given erythropoiesis-stimulating therapy)  
Bone disease Mean serum calcium <10.2 mg/dl without prescription of calcium 16.7
  Mean serum 25-hydroxyvitamin D <30 ng/ml without prescription of ergocalciferol  
  Or  
  Mean serum 25-hydroxyvitamin D >30 ng/ml and hyperparathyroidism without prescription of alfacalcidol  
Metabolic acidosis Mean serum bicarbonates <23 mEq/l without prescription of bicarbonate 60.2
Dyslipidemia Mean fasting total cholesterol >201 mg/dl or mean triglycerides >150.5 mg/dl without prescription of a lipid-lowering therapy 61.4
  1. a BP, blood pressure.