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Table 3 Risk factors during ICU stay and follow up after hospital discharge associated with mortality at 3 months

From: Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study

Characteristics Alive
(n= 38)
Dead
(n= 61)
Univariate analysis
P value; Odds Ratio [95% CI]
Day 3 (n = 77) *
SOFA score, median (IQR) 3(2-5) 6(3-9) p = 0.002; 1.26 [1.08-1.47]
Organ failures, mean ± SD 0.5 ± 0.7 1.4 ± 1.2 p = 0.002; 2.77 [1.48-5.19]
Mechanical ventilation, n (%) 12(32%) 37(61%) p = 0.003; 0.21 [0.07-0.64]
NIV, n (%) 7(18%) 9(14%) p = 0.8; 1.38 [0.39-4.86]
Shock, n (%) 3(8%) 15(25%) p = 0.06; 0.25 [0.05-1.1]
Extra-renal support, n (%) 0 14 p = 0.008*; NA
Day 7 (n = 48) **
SOFA score, median (IQR) 2(3-4) 5(4-8) p = 0.04; 1.30 [1.01-1.67]
Organ failures, mean ± SD 0.3 ± 0.6 0.9 ± 1.0 p = 0.03; 2.86 [1.09-7.53]
Mechanical ventilation, n (%) 8(21%) 25(41%) p = 0.04; 0.21 [0.05-0.094]
NIV, n (%) 3(8%) 2(3%) p = 0.53; 3.11 [0.35-31.27]
Shock, n (%) 0 3 p = 0.29*; NA
Extra-renal support, n (%) 0 9 p = 0.012*; NA
All ICU Stays (n = 99)
Mechanical ventilation, n (%) 21(55%) 47(77%) p = 0.04; 0.37 [0.14-0.97]
NIV, n (%) 18(47%) 22(36%) p = 0.37; 1.6 [0.64-3.98]
Shock, n (%) 13(34%) 37(61%) p = 0.03; 0.34 [0.13-0.86]
Extra-renal support, n (%) 3(8%) 22(36%) p = 0.003; 0.15 [0.03-0.61]
Duration of ventilation, median (IQR), days 5.2 ± 6.2 4.5 ± 9.5 p = 0.71; [0.95-1.04]
ICU length of stay, median (IQR), days 12.7 ± 18.9 16.2 ± 18.7 p = 0.38; 1.01 [0.99-1.035]
Decision to activate care withdrawal, n (%) 4(10%) 32(52%) p = 0.001; 0.11 [0.03-0.37]
After ICU discharge (n = 57)
Hospital length of stay 38.1 ± 29.6 23.6 ± 25.6 p = 0.002; 0.98 [0.97-0.99]
Hospital readmission post discharge 4 (10.5%) 6 (85.7%) p = 0.001; 0.02 [0.002-0.21]
  1. *9 and 13 patients discharged alive and dead from ICU, respectively at day 3
  2. **21 and 30 patients discharged alive and dead from ICU, respectively at day 7
  3. Sequential Organ Failure Assessment; NIV, non invasive ventilation; MV, mechanical ventilation. NA: Not applicable
  4. * by Fisher exact test