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Table 3 Risk factors during ICU stay and follow up after hospital discharge associated with mortality at 3 months

From: Predictors of mortality and short-term physical and cognitive dependence in critically ill persons 75 years and older: a prospective cohort study

Characteristics

Alive

(n= 38)

Dead

(n= 61)

Univariate analysis

P value; Odds Ratio [95% CI]

Day 3 (n = 77) *

SOFA score, median (IQR)

3(2-5)

6(3-9)

p = 0.002; 1.26 [1.08-1.47]

Organ failures, mean ± SD

0.5 ± 0.7

1.4 ± 1.2

p = 0.002; 2.77 [1.48-5.19]

Mechanical ventilation, n (%)

12(32%)

37(61%)

p = 0.003; 0.21 [0.07-0.64]

NIV, n (%)

7(18%)

9(14%)

p = 0.8; 1.38 [0.39-4.86]

Shock, n (%)

3(8%)

15(25%)

p = 0.06; 0.25 [0.05-1.1]

Extra-renal support, n (%)

0

14

p = 0.008*; NA

Day 7 (n = 48) **

SOFA score, median (IQR)

2(3-4)

5(4-8)

p = 0.04; 1.30 [1.01-1.67]

Organ failures, mean ± SD

0.3 ± 0.6

0.9 ± 1.0

p = 0.03; 2.86 [1.09-7.53]

Mechanical ventilation, n (%)

8(21%)

25(41%)

p = 0.04; 0.21 [0.05-0.094]

NIV, n (%)

3(8%)

2(3%)

p = 0.53; 3.11 [0.35-31.27]

Shock, n (%)

0

3

p = 0.29*; NA

Extra-renal support, n (%)

0

9

p = 0.012*; NA

All ICU Stays (n = 99)

Mechanical ventilation, n (%)

21(55%)

47(77%)

p = 0.04; 0.37 [0.14-0.97]

NIV, n (%)

18(47%)

22(36%)

p = 0.37; 1.6 [0.64-3.98]

Shock, n (%)

13(34%)

37(61%)

p = 0.03; 0.34 [0.13-0.86]

Extra-renal support, n (%)

3(8%)

22(36%)

p = 0.003; 0.15 [0.03-0.61]

Duration of ventilation, median (IQR), days

5.2 ± 6.2

4.5 ± 9.5

p = 0.71; [0.95-1.04]

ICU length of stay, median (IQR), days

12.7 ± 18.9

16.2 ± 18.7

p = 0.38; 1.01 [0.99-1.035]

Decision to activate care withdrawal, n (%)

4(10%)

32(52%)

p = 0.001; 0.11 [0.03-0.37]

After ICU discharge (n = 57)

Hospital length of stay

38.1 ± 29.6

23.6 ± 25.6

p = 0.002; 0.98 [0.97-0.99]

Hospital readmission post discharge

4 (10.5%)

6 (85.7%)

p = 0.001; 0.02 [0.002-0.21]

  1. *9 and 13 patients discharged alive and dead from ICU, respectively at day 3
  2. **21 and 30 patients discharged alive and dead from ICU, respectively at day 7
  3. Sequential Organ Failure Assessment; NIV, non invasive ventilation; MV, mechanical ventilation. NA: Not applicable
  4. * by Fisher exact test