Validation of the Japanese version of the Pediatric Quality of Life Inventory (PedsQL) Cancer Module

Table 12 Clinical validity of the PedsQL Cancer Module: Comparison of scores by treatment status

PedsQL Subscales	Children				Parents
	Mean n Rank	Difference	Kruskal Wallis Test	P value	Mean n Rank	Difference	Kruskal Wallis Test	P value
Pain and hurt		a,c**	10.392	0.006		a,c**, b,c	21.296	0.000
On Tx_(a)	63 85.63				87 97.70
Off Tx = < 12_(b)	27 91.06				33 113.92
Off Tx > 12_(c)	110 111.33				120 138.84
Nausea		a,c*, b,c*	66.648	0.000		a,b, b,c, a,c*	88.814	0.000
On Tx_(a)	64 61.97				82 68.57
Off Tx = < 12_(b)	26 74.13				32 99.81
Off Tx > 12_(c)	107 127.19				117 153.67
Procedural anxiety		a,c**	8.225	0.016		a,c**, b,c	12.438	0.002
On Tx_(a)	65 86.58				85 103.49
Off Tx = < 12_(b)	27 94.31				33 107.65
Off Tx > 12_(c)	109 111.25				122 135.82
Treatment anxiety			3.279	0.194		a,b, a,c**	12.013	0.002
On Tx_(a)	64 99.73				84 100.32
Off Tx = < 12_(b)	27 88.19				33 127.80
Off Tx > 12_(c)	110 104.88				122 131.44
Worry		a,c**, b,c	26.914	0.000		a,c***	14.792	0.001
On Tx_(a)	63 73.54				85 100.80
Off Tx = < 12_(b)	27 89.44				33 112.21
Off Tx > 12_(c)	110 118.65				122 136.47
Cognitive problems			1.367	0.505			3.323	0.190
On Tx_(a)	63 93.13				86 110.42
Off Tx = < 12_(b)	27 101.78				33 131.41
Off Tx > 12_(c)	109 103.53				122 125.64
Perceived physical appearance			1.287	0.525		a,c*	4.944	0.084
On Tx_(a)	65 96.07				86 109.20
Off Tx = < 12_(b)	27 97.52				33 117.06
Off Tx > 12_(c)	110 105.69				122 130.38
Communication		a,c*	6.392	0.041		a,c***	11.325	0.003
On Tx_(a)	65 90.70				84 102.44
Off Tx = < 12_(b)	27 89.17				33 111.58
Off Tx > 12_(c)	110 110.91				122 134.37

On Tx: on treatment sample; Off Tx = < 12: off treatment = < 12 months sample; Off Tx > 12: off treatment > 12 months sample.
* P < 0.05, **P = < 0.01, ***P = < 0.001 by Mann-Whitney U test.

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