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Table 5 One-way ANOVA comparing HRQOL (generic scale and cancer scale) between children on- and off-treatment (≤ 12 months or > 12 months): self- and proxy-report (bold)

From: Measuring health-related quality of life in children with cancer living in mainland China: feasibility, reliability and validity of the Chinese mandarin version of PedsQL 4.0 Generic Core Scales and 3.0 Cancer Module

Scales

Child On-treatment (a)

Child off-treatment (b)

Child off-treatment (c)

Difference

F

P

   

≤ 12 months

> 12 months

  

Value

 

n

mean (SD)

n

Mean (SD)

n

Mean (SD)

   

Generic Scale

         

   Total score

110

65.42 (16.98)

26

67.14 (18.05)

66

73.69 (16.19)

a < c**

5.04

0.007

 

157

62.33 (16.70)

35

65.92 (19.43)

74

71.22 (17.92)

a < c***

6.58

0.002

   Physical functioning

110

62.57 (21.08)

26

67.12 (18.25)

66

76.26 (19.24)

a < c***, b < c*

9.53

0.000

 

157

61.55 (18.67)

35

66.18 (20.63)

74

75.51 (21.15)

a < c***, b < c*

12.7

0.000

   Psychosocial functioning

110

67.94 (17.53)

26

67.23 (19.77)

66

72.20 (18.92)

 

1.30

0.275

 

157

63.07 (19.40)

35

66.04 (17.36)

74

68.87 (18.56)

 

2.42

0.091

   Emotional functioning

110

64.71 (19.54)

26

67.36 (22.81)

66

73.64 (20.16)

a < c**

4.05

0.019

 

157

59.82 (24.58)

35

68.40 (21.82)

74

70.71 (18.44)

a < b*, a < c***

6.44

0.002

   Social functioning

110

77.97 (17.48)

26

75.03 (18.24)

66

79.30 (15.68)

 

0.59

0.556

 

157

72.02 (20.68)

35

72.26 (18.52)

74

75.16 (18.79)

 

0.65

0.524

   School functioning

86

58.47 (19.89)

20

60.35 (18.55)

59

65.18 (23.09)

 

1.81

0.167

 

107

57.96 (19.30)

26

60.80 (22.25)

62

62.94 (24.35)

 

1.08

0.342

Cancer scale

         

   Pain and hurt

110

70.23 (20.54)

26

75.35 (20.19)

66

78.66 (22.47)

a < c*

3.38

0.036

 

157

74.68 (19.03)

35

77.81 (21.45)

74

82.12 (20.60)

a < c**

3.57

0.029

   Nausea

110

63.92 (22.36)

26

78.72 (19.11)

66

83.20 (18.59)

a < b**, a < c***

19.22

0.000

 

157

66.81 (18.29)

35

72.34 (23.05)

74

81.72 (16.14)

a < c***, b < c*

16.5

0.000

   Procedural anxiety

110

63.17 (28.31)

26

70.29(25.25)

66

73.33 (24.90)

a < c*

3.12

0.046

 

157

62.42 (22.63)

35

64.71 (25.39)

74

76.26 (24.87)

a < c***, b < c*

8.74

0.000

   Treatment anxiety

110

68.77 (23.48)

26

72.11 (26.23)

66

73.84 (20.64)

 

1.05

0.352

 

157

62.85 (20.69)

35

68.05 (24.38)

74

72.97 (23.38)

a < c**

5.46

0.005

   Worry

110

66.59 (23.24)

26

70.33 (28.10)

66

71.32 (25.61)

 

0.83

0.438

 

155

59.13 (22.00)

35

60.78 (24.43)

72

67.20 (24.74)

a < c*

3.06

0.049

   Cognitive problems

108

70.09 (25.65)

26

73.83 (30.02)

66

71.75 (29.45)

 

0.22

0.804

 

154

72.11 (23.96)

34

74.44 (29.12)

72

74.25 (26.92)

 

0.23

0.791

   Perceived physical appearance

110

74.85 (19.48)

26

76.98 (22.17)

66

79.65 (18.34)

 

1.24

0.291

 

154

77.21 (16.90)

34

74.93 (20.55)

73

75.77 (17.49)

 

0.32

0.723

   Communication

110

72.66 (19.11)

26

73.27 (18.40)

65

70.98 (22.75)

 

0.18

0.832

 

155

71.18 (22.83)

35

75.29 (24.52)

72

72.04 (22.38)

 

0.46

0.633

  1. *P < 0.05, **P < 0.01, ***P < 0.001 based on Tukey Honestly Significantly Different post hoc analysis.