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Table 2 Patient characteristics (n = 318); values represent numbers (percentages) of patients unless stated otherwise

From: Patient- and provider-related determinants of generic and specific health-related quality of life of patients with chronic systolic heart failure in primary care: a cross-sectional study

Trials source (participation in TTT- vs. HICMan-trial) 168/150 (52.8/47.2)
Sociodemographic characteristics  
   Male sex 227 (71.4)
   Mean (SD) age (years) 69.0 (10.4)
   Social class*: (n = 277)
lower 117 (36.8)
middle 135 (42.5)
upper 25 (7.9)
Clinical variables  
   NYHA-functional class (according to GP)  
I 4 (1.3)
II 185 (58.2)
III 124 (39.0)
IV 5 (1.6)
   Mean (SD) LVEF (n = 304) 35.3 (7.2)
LVEF not reported 14 (4.4)
≤ 45% 221 (69.5)
≤ 30% 83 (26.1)
   Main cause of CHF  
ischemic 143 (45.0)
non-ischemic 175 (55.0)
   Mean (SD) duration (years) of CHF (n = 238) 5.8 (5.1)
   Cardiovascular interventions  
PTCA/Stent (any) 105 (33.0)
CABG (any) 72 (22.6)
Pacemaker (right ventricular) 44 (13.8)
Pacemaker (biventricular) 19 (6.0)
ICD 49 (15.4)
Prosthetic heart valve (any) 20 (6.3)
Reanimation/Defibrillation 22 (6.9)
   Medical conditions  
Angina pectoris 81 (25.5)
PAD 55 (17.3)
Cerebrovascular disease 60 (18.9)
Hypertension 251 (78.9)
Diabetes mellitus 116 (36.5)
COPD 75 (23.6)
Depression (as rated by GP) 66 (20.8)
   Creatinine-Clearance (n = 314): Mean (SD) GFR (ml/min)** 71.2 (31.1)
Stage of renal dysfunction  
GFR ≥ 60 ml/min 182 (57.2)
GFR 30-59 ml/min 119 (37.4)
GFR ≤ 29 ml/min 13 (4.0)
   Mean level of NT-pro-BNP*** (SD) in pg/ml (n = 303) 2298.4 (3985.9)
   Mean (SD) Comorbidity (CIRS-G)**** 23.8 (5.5)
Psychosocial and behavioural characteristics  
   Depression (PHQ-9-D)  
Mean (SD) summary score 7.2 (5.4)
Major Depressive Syndrome 41 (12.9)
   Mean number (SD) of drinks per week 4.2 (6.4)
   Ex-/smoker (Ex: since at least 6 months) 142/46 (44.7/14.5)
   Heart failure self-care behaviour (EHFScB scale*****) 24.7 (7.6)
Prescribed drugs  
   ACE inhibitor 243 (76.4)
   A2RA 62 (19.5)
   β-blocker 246 (77.4)
   Spironolactone/Eplerenone (Aldosterone- antagonists) 89 (28.0)
   Loop diuretics 195 (61.3)
  1. **Social Class according to modified German Winkler-index [43] (lower class: 0-7; middle class: 8-14; upper class: 15-21);
  2. NYHA, New York Heart Association; LVEF, Left ventricular ejection fraction; CHF, Chronic (systolic) heart failure; CHD, Coronary heart disease; PTCA, Percutaneous Transluminal Coronary Angioplasty; CABG, Coronary artery bypass graft surgery; ICD, Implantable cardioverter defibrillator; PAD, Peripheral arterial disease; COPD, Chronic obstructive pulmonary disease;
  3. **Estimation of the GFR according to the formula of Cockroft and Gault;
  4. ***N-terminal Brain Natriuretic Peptide;
  5. ****CIRS-G, Cumulative illness (physician) rating scale, range 0-56, lower scores imply less impairment of 14 body systems
  6. *****European Self-care Behaviour scale, range 12-60, lower scores imply better self-care behaviour;
  7. ACE = angiotensin converting enzyme; A2RA = angiotensin-2 receptor antagonist