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Table 2 Patient characteristics (n = 318); values represent numbers (percentages) of patients unless stated otherwise

From: Patient- and provider-related determinants of generic and specific health-related quality of life of patients with chronic systolic heart failure in primary care: a cross-sectional study

Trials source (participation in TTT- vs. HICMan-trial)

168/150 (52.8/47.2)

Sociodemographic characteristics

 

   Male sex

227 (71.4)

   Mean (SD) age (years)

69.0 (10.4)

   Social class*:

(n = 277)

lower

117 (36.8)

middle

135 (42.5)

upper

25 (7.9)

Clinical variables

 

   NYHA-functional class (according to GP)

 

I

4 (1.3)

II

185 (58.2)

III

124 (39.0)

IV

5 (1.6)

   Mean (SD) LVEF (n = 304)

35.3 (7.2)

LVEF not reported

14 (4.4)

≤ 45%

221 (69.5)

≤ 30%

83 (26.1)

   Main cause of CHF

 

ischemic

143 (45.0)

non-ischemic

175 (55.0)

   Mean (SD) duration (years) of CHF (n = 238)

5.8 (5.1)

   Cardiovascular interventions

 

PTCA/Stent (any)

105 (33.0)

CABG (any)

72 (22.6)

Pacemaker (right ventricular)

44 (13.8)

Pacemaker (biventricular)

19 (6.0)

ICD

49 (15.4)

Prosthetic heart valve (any)

20 (6.3)

Reanimation/Defibrillation

22 (6.9)

   Medical conditions

 

Angina pectoris

81 (25.5)

PAD

55 (17.3)

Cerebrovascular disease

60 (18.9)

Hypertension

251 (78.9)

Diabetes mellitus

116 (36.5)

COPD

75 (23.6)

Depression (as rated by GP)

66 (20.8)

   Creatinine-Clearance (n = 314): Mean (SD) GFR (ml/min)**

71.2 (31.1)

Stage of renal dysfunction

 

GFR ≥ 60 ml/min

182 (57.2)

GFR 30-59 ml/min

119 (37.4)

GFR ≤ 29 ml/min

13 (4.0)

   Mean level of NT-pro-BNP*** (SD) in pg/ml (n = 303)

2298.4 (3985.9)

   Mean (SD) Comorbidity (CIRS-G)****

23.8 (5.5)

Psychosocial and behavioural characteristics

 

   Depression (PHQ-9-D)

 

Mean (SD) summary score

7.2 (5.4)

Major Depressive Syndrome

41 (12.9)

   Mean number (SD) of drinks per week

4.2 (6.4)

   Ex-/smoker (Ex: since at least 6 months)

142/46 (44.7/14.5)

   Heart failure self-care behaviour (EHFScB scale*****)

24.7 (7.6)

Prescribed drugs

 

   ACE inhibitor

243 (76.4)

   A2RA

62 (19.5)

   β-blocker

246 (77.4)

   Spironolactone/Eplerenone (Aldosterone- antagonists)

89 (28.0)

   Loop diuretics

195 (61.3)

  1. **Social Class according to modified German Winkler-index [43] (lower class: 0-7; middle class: 8-14; upper class: 15-21);
  2. NYHA, New York Heart Association; LVEF, Left ventricular ejection fraction; CHF, Chronic (systolic) heart failure; CHD, Coronary heart disease; PTCA, Percutaneous Transluminal Coronary Angioplasty; CABG, Coronary artery bypass graft surgery; ICD, Implantable cardioverter defibrillator; PAD, Peripheral arterial disease; COPD, Chronic obstructive pulmonary disease;
  3. **Estimation of the GFR according to the formula of Cockroft and Gault;
  4. ***N-terminal Brain Natriuretic Peptide;
  5. ****CIRS-G, Cumulative illness (physician) rating scale, range 0-56, lower scores imply less impairment of 14 body systems
  6. *****European Self-care Behaviour scale, range 12-60, lower scores imply better self-care behaviour;
  7. ACE = angiotensin converting enzyme; A2RA = angiotensin-2 receptor antagonist
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Health and Quality of Life Outcomes

ISSN: 1477-7525

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