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Table 2 Mean scores on the 12 MSQOL-54 subscales and the two composite scores for the total sample, by gender and by ambulation status (the latter two adjusted for effects of age and disease duration)

From: Disability status and quality of life in multiple sclerosis: non-linearity of the Expanded Disability Status Scale (EDSS)

  

Gender

Level of ambulation

 

Total Sample

Men

Women

Group 1

Group 2

Group 3

Physical function

44.0 +/- 33.9

37.7 +/- 22.1

37.1 +/- 23.2

67.9 +/- 26.1b,c

28.9 +/- 23.4b,d

15.4 +/- 23.3d,c

Role (physical)

35.8 +/- 40.6

35.0 +/- 37.9 a

30.0 +/- 40.2 a

51.2 +/- 44.9b,c

25.5 +/- 40.3b

20.9 +/- 40.1c

Role (emotional)

58.2 +/- 44.5

58.8 +/- 45.4

57.0 +/- 48.6

64.6 +/- 53.6c

57.1 +/- 48.0

52.1 +/- 47.5c

Pain

65.4 +/- 29.2

69.9 +/- 28.4 a

62.5 +/- 29.6 a

72.2 +/- 33.7b,c

65.5 +/- 30.0b

60.8 +/- 30.4c

Emotional well-being

61.3 +/- 20.1

62.1 +/- 21.2

60.6 +/- 22.0

64.0 +/- 25.0b,c

60.2 +/- 22.4b

59.9 +/- 22.5c

Energy

39.7 +/- 19.8

39.7 +/- 20.3

38.3 +/- 21.1

44.9 +/- 24.1b,c

37.0 +/- 21.6b

35.1 +/- 21.7c

Health perceptions

43.9 +/- 18.9

41.4 +/- 19.0

43.2 +/- 19.8

48.9 +/- 22.5b,c

40.2 +/- 20.1b

37.9 +/- 20.3c

Social function

65.1 +/- 24.9

63.0 +/- 23.5

63.7 +/- 24.4

75.2 +/- 27.8b,c

61.0 +/- 24.7b,d

53.8 +/- 25.1d,c

Cognitive function

68.4 +/- 22.9

66.5 +/- 24.0

69.1 +/- 24.9

69.0 +/- 28.4

68.2 +/- 25.4

66.3 +/- 25.7

Health distress

62.8 +/- 21.9

61.7 +/- 22.2

61.7 +/- 23.1

69.6 +/- 26.3b,c

59.3 +/- 23.5b

56.3 +/- 23.7c

Overall quality of life

58.0 +/- 24.5

55.0 +/- 23.0

56.2 +/- 24.0

66.8 +/- 27.2b,c

53.9 +/- 24.3b,d

46.1 +/- 24.6d,c

Sexual function

61.2 +/- 33.6

52.6 +/- 31.6 a

65.0 +/- 33.2 a

68.1 +/- 35.9b,c

57.7 +/- 32.3b,d

50.6 +/- 32.6d,c

physical health composite

52.7 +/- 19.7

49.6 +/- 16.9

48.9 +/- 18.3

62.5 +/- 19.1b,c

45.5 +/- 17.2b,d

39.8 +/- 17.2d,c

mental health composite

62.0 +/- 21.3

61.1 +/- 22.0

60.6 +/- 23.6

66.3 +/- 25.8b,c

59.6 +/- 23.1b

56.7 +/- 22.9c

  1. ap < .01 men vs. women (ANCOVA)
  2. bp < .01 group 1 vs. group 2 (ANCOVA)
  3. cp < .01 group 1 vs. group 3 (ANCOVA)
  4. dp < .01 group 2 vs. group 3 (ANCOVA)