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Table 5 Results of multiple variable modelling in the estimation dataset

From: Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease

Model

1

2

3

4

5

6

7

8

9

10

11

12

Sample size

2844

1345

2492

1108

1801

1186

2303

1186

1189

1189

1106

1104

Age per year

0.002

0.008

0.001

0.003

0.002

0.003

0.0004

0.002

-0.001

0.002

0.002

0.002

 

(0.001, 0.004)

(0.006, 0.009)

(0.0002, 0.002)

(0.002, 0.005)

(0.0004, 0.003)

(0.001, 0.004)

(-0.001, 0.002)

(0.001, 0.003)

(-0.002, 0.001)

(0.0004, 0.003)

(0.001, 0.003)

(0.001, 0.003)

Sex = male

0.054

-0.031

0.038

-0.012

0.031

0.034

0.035

0.019

0.013

0.029

-0.009

-0.009

 

(0.029, 0.078)

(-0.061, -0.002)

(0.015, 0.061)

(-0.037, 0.012)

(0.003, 0.059)

(0.004, 0.064)

(0.013, 0.058)

(-0.007, 0.046)

(-0.013, 0.039)

(-0.001, 0.059)

(-0.033, 0.014)

(-0.033, 0.014)

MM

0.117

0.111

0.043

0.016

0.123

0.133

0.053

0.049

0.089

0.132

0.021

0.023

 

(0.091, 0.142)

(0.079, 0.142)

(0.018, 0.068)

(-0.015, 0.046)

(0.091, 0.154)

(0.098, 0.169)

(0.027, 0.078)

(0.016, 0.083)

(0.057, 0.121)

(0.095, 0.168)

(-0.009, 0.050)

(-0.007, 0.052)

Pre PCI

0.165

0.134

0.107

0.022

0.181

0.130

0.152

0.089

0.117

0.120

0.048

0.047

 

(0.110, 0.221)

(0.086, 0.181)

(0.057, 0.157)

(-0.020, 0.064)

(0.127, 0.235)

(0.079, 0.181)

(0.103, 0.200)

(0.043, 0.135)

(0.072, 0.161)

(0.069, 0.172)

(0.008, 0.088)

(0.007, 0.087)

Post PCI

0.101

0.127

0.036

0.027

0.084

0.116

0.037

0.047

0.076

0.129

0.018

0.015

 

(0.068, 0.134)

(0.082, 0.172)

(0.004, 0.067)

(-0.013, 0.067)

(0.043, 0.125)

(0.068, 0.165)

(0.006, 0.068)

(0.003, 0.092)

(0.033, 0.119)

(0.080, 0.178)

(-0.021, 0.056)

(-0.023, 0053)

Pre CABG*

0.151

0.146

0.132

0.048

0.178

0.124

0.186

0.120

0.113

0.117

0.073

0.071

 

(0.079, 0.223)

(0.087, 0.205)

(0.069, 0.195)

(-0.004, 0.100)

(0.108, 0.248)

(0.060, 0.188)

(0.122, 0.249)

(0.063, 0.177)

(0.057, 0.169)

(0.053, 0.182)

(0.024, 0.123)

(0.022, 0.121)

ETT per minute

 

0.027

          
  

(0.024, 0.030)

          

CCS**

            

   0

  

0.426

         
   

(0.391, 0.461)

         

   I

  

0.395

         
   

(0.360, 0.430)

         

   II

  

0.307

         
   

(0.274, 0.340)

         

   III

  

0.114

         
   

(0.077, 0.152)

         

ECS**

   

0.0062

      

0.0036

0.0036

    

(0.0057, 0.0066)

      

(0.0030, 0.0042)

(0.0030, 0.0042)

ASS

    

0.0032

       
     

(0.0027, 0.0037)

       

ASS (ACRE excluded)

     

0.0031

     

0.0004

      

(0.0025, 0.0036)

     

(-0.0001, 0.0008)

AFS

      

0.0046

     
       

(0.0043, 0.0050)

     

AFS (ACRE excluded)

       

0.0047

  

0.0015

0.0014

        

(0.0043, 0.0051)

  

(0.0010, 0.0020)

(0.0008, 0.0020)

DPS

        

0.0055

 

0.0021

0.0018

         

(0.0050, 0.0060)

 

(0.0015, 0.0027)

(0.0012, 0.0024)

TSS

         

0.0043

 

0.0010

          

(0.0035, 0.0052)

 

(0.0002, 0.0017)

  1. *CABG also includes SCS (spinal cord stimulation) and laser (percutaneous or transmyocardial laser revascularization ) treatments. Reference category - Post CABG.
  2. **Reference category, class IV.
  3. ***All SAQ score parameter estimates are for a one point increase in the score for the given scale.
  4. Key: MM = medical management, PCI = balloon angioplasty ± stent, CABG = coronary artery bypass graft, ETT = exercise treadmill time, CCS = Canadian Cardiovascular Society Angina Classification, ECS = exertional capacity scale, ASS = anginal stability scale, ACRE = Appropriateness for coronary revascularization, AFS = anginal frequency scale, DPS = disease perception scale, TSS = treatment satisfaction scale