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Table 3 Minimal Important Difference of the TRIM-Weight

From: Development and validation of the Treatment Related Impact Measure of Weight (TRIM-Weight)

  Mean N Mean N Difference 1/2 SD
TRIM-Weight Domain A little   Somewhat    
Overall, how much does your weight loss medication impact your daily life?
Daily Life 79.2 (15.2) 62 63.1 (21.9) 45 16.1 7.6
Overall, how well does your weight loss medication work? (reverse)
  A little   Somewhat    
Weight Management 35.4 (15.5) 20 47.0 (13.9) 64 11.6 7.0
Overall, how convenient is your weight loss medication? (reverse)
  A little   Somewhat    
Treatment Burden 41.7 (15.4) 15 54.8 (14.4) 38 13.1 7.2
Overall, how much do side effects from your weight loss medication negatively impact you?
  A little   Somewhat    
Experience of Side Effects 66.3 (16.7) 59 51.7 (18.3) 45 14.6 8.4
Overall, how much does your weight loss medication negatively impact your psychological health?
  A little   Somewhat    
Psychological Health 60.3 (20.9) 45 50.0 (20.4) 36 10.3 10.5
Overall, how well does your weight loss medication work?
  No impact at all   Slightly positive impact    
TRIM-Weight Total 63.9 (21.1) 24 72.4 (14.4) 63 8.5 7.2