MACCE n = 52 | All-cause mortality n = 59 | |||||
---|---|---|---|---|---|---|
n* | % | HR | p-value | HR | p-value | |
Socio-demographics: | ||||||
Mean age in years (SD) | 72 (5) | 1.05 | 0.131 | 1.06 | 0.044 | |
Cohabitation status | 0.007 | <0.001 | ||||
- Living alone | 60 | 41 | 2.12 | 2.87 | ||
- Cohabitation | 85 | 59 | (ref) | (ref) | ||
Marital status | 0.003 | 0.009 | ||||
- Divorced | 7 | 5 | 4.57 | 0.007 | 3.20 | 0.036 |
- Widowed | 62 | 43 | 2.76 | 0.001 | 2.61 | 0.001 |
- Unmarried | 6 | 4 | 0.84 | 0.868 | 2.71 | 0.111 |
- Married | 68 | 48 | (ref) | (ref) | ||
Educational status | 0.085 | 0.098 | ||||
- Elementary school | 61 | 44 | (ref) | |||
- Secondary school | 41 | 29 | 1.09 | 0.804 | 1.29 | 0.441 |
- High school and university/college | 37 | 27 | 2.00 | 0.039 | 1.99 | 0.032 |
Clinical characteristics: | ||||||
Risk factors of CAD | ||||||
- Mean total cholesterol, mmol/L (SD) | 7.0 (1.4) | 1.10 | 0.400 | 1.05 | 0.660 | |
- Hypertension | 53 | 37 | 0.96 | 0.877 | 1.30 | 0.318 |
- Diabetes mellitus | 17 | 12 | 1.74 | 0.130 | 1.22 | 0.607 |
- Overweight | 42 | 39 | 0.90 | 0.740 | 1.14 | 0.665 |
- Family history of CAD | 59 | 68 | 1.85 | 0.152 | 2.06 | 0.115 |
- Smoking habits | 0.531 | 0.817 | ||||
- Non smoker | 68 | 55 | 1.24 | 0.528 | 1.16 | 0.674 |
- Ex-smoker | 21 | 17 | 0.77 | 0.607 | 1.31 | 0.528 |
- Current smoker | 34 | 28 | (ref) | (ref) | ||
Previous angina | 62 | 45 | 1.27 | 0.397 | 1.23 | 0.441 |
Previous acute MI | 32 | 23 | 1.09 | 0.788 | 1.11 | 0.734 |
Mean time since MI in months (SD) † | 29 (16) | 1.01 | 0.333 | 1.01 | 0.398 | |
Disease severity | ||||||
- Mean max CK (SD) | 1099 (1000) | 1.00 | 0.540 | 1.00 | 0.744 | |
- Q in ECG | 63 | 44 | 0.83 | 0.502 | 1.22 | 0.447 |
- Left ventricular ejection fraction | 0.108 | 0.012 | ||||
- >60% | 78 | 62 | (ref) | (ref) | ||
- 30-60% | 45 | 36 | 0.97 | 0.926 | 1.19 | 0.568 |
- <30% | 2 | 2 | 4.69 | 0.038 | 9.88 | 0.003 |
Mean creatinine, μmol/L (SD) ‡ | 92.5 (18.9) | 1.07 | 0.386 | 1.18 | 0.028 | |
Treatment during index MI | 0.258 | 0.793 | ||||
- Medical treatment | 92 | 66 | 0.43 | 0.164 | 1.99 | 0.497 |
- Thrombolysis | 43 | 31 | 0.35 | 0.100 | 1.95 | 0.517 |
- PCI/CABG | 4 | 3 | (ref) | (ref) | ||
Medication at discharge after index MI | ||||||
- Beta blockers | 98 | 69 | 0.50 | 0.015 | 0.77 | 0.340 |
- Calcium antagonists | 18 | 13 | 0.47 | 0.199 | 1.11 | 0.789 |
- ACE inhibitors | 40 | 28 | 1.44 | 0.232 | 1.36 | 0.281 |
- Diuretics | 48 | 34 | 1.60 | 0.109 | 1.66 | 0.060 |
- Digitalis | 9 | 6 | 1.97 | 0.152 | 1.19 | 0.738 |
- Antithrombotics | 123 | 86 | 1.04 | 0.924 | 1.14 | 0.730 |
- Lipid-lowering | 26 | 18 | 1.05 | 0.899 | 0.71 | 0.360 |
- Antidiabetics | 12 | 8 | 1.96 | 0.100 | 1.03 | 0.955 |