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Table 5 Responder definition estimates

From: Interpreting scores on multiple sclerosis-specific patient reported outcome measures (the PRIMUS and U-FIS)

  PRIMUS Activities PRIMUS QoL U-FIS
Responder Definition Estimates n Mean
change
score
n Mean
change
score
n Mean
change
score
Anchor-based       
Equivalent to reported EQ-5 D RD improvement 16 -2.3 17 -1.0 17 -6.5
Equivalent to reported EQ-5 D RD deterioration 15 1.8 15 1.0 15 4.7
Distribution-based       
SEM 814 1.2 812 1.5 815 2.4
Change score equivalent to 0.30 ES 814 1.4 812 1.3 815 4.2
Change score equivalent to 0.50 ES 814 2.3 812 2.2 815 7.0
  1. Distribution-based estimates were conducted at baseline