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Table 5 Responder definition estimates

From: Interpreting scores on multiple sclerosis-specific patient reported outcome measures (the PRIMUS and U-FIS)

 

PRIMUS Activities

PRIMUS QoL

U-FIS

Responder Definition Estimates

n

Mean

change

score

n

Mean

change

score

n

Mean

change

score

Anchor-based

      

Equivalent to reported EQ-5 D RD improvement

16

-2.3

17

-1.0

17

-6.5

Equivalent to reported EQ-5 D RD deterioration

15

1.8

15

1.0

15

4.7

Distribution-based

      

SEM

814

1.2

812

1.5

815

2.4

Change score equivalent to 0.30 ES

814

1.4

812

1.3

815

4.2

Change score equivalent to 0.50 ES

814

2.3

812

2.2

815

7.0

  1. Distribution-based estimates were conducted at baseline