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Table 5 HRQOL according to the mode of treatment of thyroid cancer

From: Decreased health-related quality of life in disease-free survivors of differentiated thyroid cancer in Korea

Variables Surgery
alone
(n = 25)
Surgery and
RAI < 150 mCi
(n = 174)
Surgery and
RAI < 150 mCi
(n = 117)
 
  mean (SD) mean (SD) mean (SD) P value
EORTC QLQ-C30     
   Global health status/QOL 57.99 (17.8) 57.90 (21.1) 57.97 (21.8) NS
   Physical functioning 79.93 (13.5) 73.82 (17.1) 75.65 (14.1) NS
   Role functioning 80.56 (20.6) 76.88 (22.41) 76.81 (23.7) NS
   Emotional functioning 67.36 (24.8) 68.66 (23.20) 70.42 (19.6) NS
   Cognitive functioning 76.39 (21.9) 69.85 (21.2) 74.64 (21.7) NS
   Social functioning 82.64 (25.7) 81.50 (20.5) 81.01 (22.1) NS
HADS     
   Anxiety 6.63 (3.9) 6.28 (3.8) 6.15 (3.8) NS
   Depression 6.21 (4.0) 5.80 (3.3) 6.15 (3.8) NS
BFI, mean score 4.13 (2.0) 4.36 (2.4) 4.53 (2.0) NS
  1. HRQOL, Health-related quality of life; EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30; QOL, quality of life; HADS, Hospital Anxiety and Depression Scale; BFI, Brief Fatigue Inventory; SD, standard deviation; RAI, radioactive iodine therapy; NS, not significant
  2. Each domain of EORTC QLQ-C30 are calculated and ranges from 0 to 100 and the higher score represents a better level of HRQOL.
  3. HADS; HADS-Anxiety and HADS-Depression are scored from 0 to 21, with higher scores indicating greater distress. Normal (0-7); mild disorder (8-10); moderate disorder (11-14); severe disorder (15-21).
  4. BFI; global BFI score ranges from 0 to 10, with higher scores indicating greater distress. Mild fatigue (1-3); moderate fatigue (4-6); severe fatigue (7-10).