Table 2 Agreement of patient- and proxy-ratings for the EORTC QLQ-C30
From: Do neurooncological patients and their significant others agree on quality of life ratings?
EORTC QLQ-C30 | Patient Mean (SD) | Proxy Mean (SD) | Patient minus Proxy | effect size | t-value p-value | Pearson-Correlation (CI95%) | agreement (+/- 5 points) |
|---|---|---|---|---|---|---|---|
Physical Functioning | 77.6 (27.3) | 74.3 (28.8) | 3.3 | 0.12 | t = 1.16; p = 0.25 | 0.79* (0.65-0.89) | 36% |
Social Functioning | 69.8 (35.4) | 61.1 (34.5) | 8.7 | 0.25 | t = 1.33; p = 0.19 | 0.26 (-0.05-0.53) | 21% |
Role Functioning | 63.5 (36.9) | 62.7 (35.3) | 0.8 | 0.02 | t = 0.13; p = 0.90 | 0.42* (0.13-0.65) | 31% |
Emotional Functioning | 59.5 (30.4) | 61.8 (23.8) | -2.3 | -0.08 | t = -0.45; p = 0.65 | 0.31* (0.01-0.56) | 14% |
Cognitive Functioning | 70.6 (31.2) | 70.2 (27.7) | 0.4 | 0.01 | t = 0.08; p = 0.94 | 0.36* (0.06-0.60) | 24% |
Global QOL | 63.8 (23.0) | 62.0 (21.6) | 1.8 | 0.08 | t = 0.55; p = 0.58 | 0.55* (0.29-0.74) | 24% |
Fatigue | 41.5 (32.6) | 44.2 (29.3) | -2.7 | -0.09 | t = -0.50; p = 0.62 | 0.40* (0.11-0.64) | 19% |
Nausea/Vomiting | 9.9 (16.9) | 9.1 (20.9) | 0.8 | 0.04 | t = 0.24; p = 0.81 | 0.35* (0.05-0.60) | 60% |
Pain | 15.9 (25.5) | 19.5 (22.6) | -3.7 | -0.14 | t = -0.81; p = 0.42 | 0.28 (-0.03-0.54) | 39% |
Dyspnoea | 20.6 (31.2) | 15.1 (22.3) | 5.6 | 0.20 | t = 1.19; p = 0.24 | 0.40* (0.11-0.64) | 50% |
Sleeping Disturbances | 27.8 (32.0) | 28.6 (30.0) | -0.8 | -0.03 | t = -0.17; p = 0.87 | 0.51* (0.25-0.71) | 52% |
Appetite Loss | 15.9 (27.8) | 19.0 (29.6) | -3.2 | -0.11 | t = -0.81; p = 0.42 | 0.61* (0.38-0.78) | 71% |
Constipation | 15.8 (29.8) | 15.8 (25.4) | 0.0 | 0.00 | t = 0.00; p = 1.00 | 0.50* (0.24-0.70) | 68% |
Diarrhea | 7.3 (19.0) | 11.4 (25.4) | -4.1 | -0.17 | t = -1.09; p = 0.28 | 0.46* (0.18-0.67) | 83% |
Financial Impact | 22.2 (31.8) | 19.8 (27.6) | 2.4 | 0.08 | t = 0.53; p = 0.60 | 0.53* (0.28-0.72) | 60% |
Taste Alterations | 22.1 (34.7) | 18.8 (32.5) | 3.3 | 0.10 | t = 0.93; p = 0.36 | 0.77* (0.62-0.88) | 60% |