From: Utility of WHOQOL-BREF in measuring quality of life in Sickle Cell Disease
 | 0–3 painful crises/year (N = 412) | >3 painful crises/year (N = 79) | p-value |
---|---|---|---|
WHOQOL-Physical | 14.3 (14.0, 14.5) | 12.3 (11.8,12.8) | <0.001 |
WHOQOL-Psychological | 14.3 (14.1, 14.5) | 13.6 (13.1,14.1) | 0.009 |
WHOQOL- Social Relations | 15.1 (14.8, 15.3) | 14.1 (13.4, 14.7) | 0.004 |
WHOQOL-Environmental | 13.5 (13.3, 13.7) | 12.5 (11.9, 13.1) | <0.001 |
Total WHOQOL Score | 57.2 (56.4, 57.9) | 52.6 (50.9, 54.3) | <0.001 |
SF 36-Physical Health | 26.7 (26.4, 27.0) | 25.2 (24.4, 26.0) | <0.001 |
SF36-Mental Health | 33.1 (32.6, 33.7) | 28.9 (27.5, 30.3) | <0.001 |
SF36-Role Limitations | 35.6 (35.1, 36.4) | 28.2 (26.6, 29.9) | <0.001 |
Total SF36 Score | 95.6 (94.4, 96.8) | 82.3 (78.9, 85.7) | <0.001 |
QOLS Score | 78.7 (77.6, 79.7) | 74.6 (71.9, 77.1) | 0.002 |