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Table 4 Treatment differences and effect sizes for the Sleep Quality Scale

From: Psychometric properties of a single-item scale to assess sleep quality among individuals with fibromyalgia

Pregabalin Dose Group Treatment Comparison
(Pregabalin – Placebo)a
Effect Size a
  Difference 95% CI p-value  
Study 1056     
    300 mg -0.86 -1.30, -0.43 0.0001 -0.521
    450 mg -0.97 -1.40, -0.53 <0.0001 -0.587
    600 mg -1.21 -1.64, -0.77 <0.0001 -0.732
Study 1077     
    300 mg -0.73 -1.14, -0.31 0.0007 -0.458
    450 mg -1.12 -1.54, -0.71 <0.0001 -0.703
    600 mg -1.31 -1.73, -0.90 <0.0001 -0.822
  1. CI = Confidence Interval
  2. aHigher Sleep Quality scores indicate poorer sleep quality. Therefore a negative difference between pregabalin and placebo and negative effect size indicates a greater improvement in sleep quality for patients receiving pregabalin relative to those receiving placebo.