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Table 3 Mean (SD) SF-6D, SF-36v2 and CLDQ scores by CHB groups

From: Health-related quality of life of Southern Chinese with chronic hepatitis B infection

Scores (Norm)* Uncomplicated CHB (n = 156) Impaired LF (n = 102) Cirrhosis (n = 139) HCC (n = 123) Overall (n = 520) Significant
difference
SF-6D       
Preference
(0.787)
0.755† (0.14) 0.745† (0.15) 0.701† (0.15) 0.72† (0.16) 0.73† (0.15) 1>3‡
SF-36v2       
   PF (90.6) 90.4 (13.3) 90.5 (13.0) 82.6† (16.0) 82.6† (16.6) 86.5† (15.3) 1>3, 1>4, 2>3, 2>4‡
   RP (90.2) 85.2† (19.2) 79.7† (24.2) 68.8† (29.2) 70.7† (28.8) 76.3† (26.4) 1>3, 1>4, 2>3‡
   BP (82.6) 72.9† (24.8) 70.2† (24.7) 70.3† (27.8) 71.1† (27.9) 71.2† (26.3) NA
   GH (53.2) 54.6 (20.5) 48.8† (20.7) 42.0† (22.5) 54.0 (22.1) 49.9† (22.0) 1>3, 3<4‡
   VT (60.2) 65.1† (17.6) 62.4 (19.8) 55.4† (24.9) 61.6 (22.8) 61.2 (21.7) 1>3‡
   SF (92.4) 86.3† (18.5) 82.0† (20.9) 73.7† (29.9) 74.4† (29.5) 79.3† (25.7) 1>3, 1>4‡
   RE (88.5) 83.0† (18.6) 79.3† (21.9) 75.5† (26.6) 76.8† (26.4) 78.8† (23.6) 1>3‡
   MH (72.0) 74.4 (16.1) 71.9 (20.3) 70.8 (19.3) 73.0 (20.3) 72.6 (18.8) NA
   PCS (48.8) 46.9† (9.2) 45.5† (9.6) 40.4† (11.2) 42.0† (11.5) 43.7† (10.7) 1>3, 1>4, 2>3‡
   MCS (50.9) 50.7 (9.4) 48.6 (12.0) 47.3† (13.3) 48.9 (13.7) 49.0† (12.1) NA
CLDQ       
   AS 6.3 (0.9) 6.2 (1.0) 5.8 (1.4) 5.7 (1.3) 6.0 (1.2) 1>3, 1>4, 2>4‡
   FA 5.3 (1.1) 5.0 (1.2) 4.7 (1.3) 4.9 (1.3) 5.0 (1.2) 1>3‡
   SS 5.9 (0.9) 5.7 (0.9) 5.3 (1.1) 5.5 (1.1) 5.6 (1.0) 1>3, 1>4, 2>3‡
   AC 6.3 (1.0) 6.0 (1.2) 5.6 (1.5) 5.7 (1.4) 5.9 (1.3) 1>3, 1>4‡
   EF 5.6 (1.0) 5.3 (1.2) 5.1 (1.4) 5.2 (1.3) 5.3 (1.2) 1>3‡
   WO 5.9 (1.2) 5.5 (1.3) 5.0 (1.7) 5.5 (1.4) 5.5 (1.5) 1>2, 1>3‡
   Overall 5.9 (0.8) 5.6 (0.9) 5.3 (1.1) 5.4 (1.0) 5.6 (1.0) 1>3, 1>4, 2>3‡
  1. CHB = Chronic Hepatitis B; LF = Liver Function; HCC = Hepatocellular Carcinoma; PF = Physical Functioning; RP = Role Physical; BP = Bodily Pain; GH = General Health; VT = Vitality; SF = Social Functioning; RE = Role Emotional; MH = Mental Health, PCS = Physical Component Summary Score; MCS = Mental Component Summary Score; AS = Abdominal Symptoms; FA = Fatigue; SS = Systemic Symptoms; AC = Activity; EF = Emotional Function; WO = Worry.
  2. Notes:
  3. *The mean scale and summary scores of adults >40 years old derived from the 1998 HK general population study.
  4. † Significance difference between CHB groups (overall) and HK norm (p < 0.05).
  5. ‡ Significant difference between four CHB groups (p < 0.05). Group 1, uncomplicated CHB; group 2, Impaired LF; group 3, Cirrhosis; and group 4, HCC.