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Table 6 Regression algorithms for converting NIHSS data into AQoL scores

From: Can we derive an 'exchange rate' between descriptive and preference-based outcome measures for stroke? Results from the transfer to utility (TTU) technique

Model Predictor β SE t Sig.
NIHSS Index      
All stroke (Constant) 0.4639 0.0044 104.97 0.000
  NIHSS 0.0024 0.0020 1.20 0.230
  NIHSS*NIHSS -0.0000 0.0000 -1.22 0.224
  0.7856   F849,1718 = 8.45 0.000
   Obs = 1302 Ids = 705 F2,595 = 1.35 0.259
    R2 within = 0.00 R2 between = 0.17 R2 overall = 0.12
NIHSS = 0–5 (Constant) 0.4754 0.0066 72.07 0.000
  NIHSS 0.0802 0.0178 4.52 0.000
  NIHSS*NIHSS -0.0170 0.0046 -3.68 0.000
  0.7955   F652,540 = 6.27 0.000
   Obs = 1195 Ids = 653 F2,540 = 11.41 0.000
    R2 within = 0.04 R2 between = 0.00 R2 overall = 0.00
NIHSS ≥ 6 (Constant) 0.2882 0.0874 3.30 0.001
  NIHSS -0.0247 0.0133 -1.85 0.064
  NIHSS*NIHSS 0.0005 0.0004 1.19 0.234
  0.7680 - - -
   Obs = 103 Ids = 88 Wald χ2 = 11.58 0.003
    R2 within = 0.00 R2 between = 0.12 R2 overall = 0.12
NIHSS Item      
All stroke (Constant) 0.4499 0.0059 76.81 0.000
  Visual fields -0.0475 0.0232 -2.05 4.53
  Facial weakness 0.0909 0.0201 4.53 0.000
  0.8103   F704,595 = 6.86 0.000
   Obs = 1302 Ids = 705 F2,595 = 10.89 0.000
    R2 within = 0.04 R2 between = 0.03 R2 overall = 0.01
NIHSS = 0–5 (Constant) 0.4810 0.0055 88.15 0.000
  Facial weakness 0.0984 0.0232 4.24 0.000
  Limb ataxia 0.0630 0.0273 2.31 0.021
  0.7984   F652,540 = 6.67 0.000
   Obs = 1195 Ids = 653 F2,540 = 12.42 0.000
    R2 within = 0.04 R2 between = 0.01 R2 overall = 0.01
NIHSS ≥ 6 (Constant) 0.0732 0.0496 1.48 0.191
  Consciousness -0.3052 0.0572 -5.34 0.002
  Eye movements 0.3073 0.0846 3.63 0.011
  Facial weakness -0.1033 0.0263 -3.93 0.008
  Motor – Left arm 0.0760 0.0208 3.65 0.011
  Motor – Right leg -0.3157 0.0364 -8.66 0.000
  Motor – Left leg 0.2980 0.0415 7.18 0.000
  Sensory -0.1340 0.0310 -4.33 0.005
  Language 0.1336 0.0319 4.19 0.006
  Extinction/Inattention -0.1198 0.0270 -4.44 0.004
  0.6653   F87,6 = 32.07 0.000
   Obs = 103 Ids = 88 F9,6 = 10.36 0.005
    R2 within = 0.94 R2 between = 0.05 R2 overall = 0.05