Skip to main content

Table 7 Studies on relationship between quality of life data and survival in patients with melanoma

From: Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008

Author(s) Year Sample HRQOL measure(s) Results*
Cassileth et al. [12, 86] 1985 and 1988 359 unresectable cancers or early stage melanoma or breast cancer Social and psychological factors Social and psychological factors individually or in combined did not influence the length of survival.
Coates et al. [87] 1993 152 metastatic melanoma LASA scales + Spitzer QLI QLI and LASA scores for mood, appetite, and overall QOL were significant predictors of survival.
Butow et al. [88] 1999 125 metastatic melanoma Cognitive appraisal of threat + coping + psychological adjustment + perceived aim of treatment + social support + QOL Perceived aim of treatment, minimization, anger and better QOL were independently predictive of longer survival.
Brown et al. [89] 2000 426 early stage melanoma 3 single-item LASA scales measuring physical well-being, mood and perceived effort to cope Shorter survival duration was associated with a positive mood (On average patients who relapsed or died reported using more active, distraction or avoidant styles of coping).
Chiarion-Sileni et al. [90] 2003 140 advanced melanoma RSCL Baseline overall QOL and the physical symptom distress scores were significant independent prognostic factors for survival.
Lehto et al. [91] 2007 59 localized melanoma Coping with cancer + anger expression + perceived social support + life stresses + domains of QOL Anger non-expression, hopelessness, over-positive reporting of QOL reduced survival while denial/minimizing response to the diagnosis as such predicted longer survival.
  1. Abbreviations: LASA: Linear Analog Self Assessment; QLI; Quality of Life Index; QOL: quality of life; RSCL: Rotterdam Symptom Checklist
  2. * All results obtained from multivariate analyses after controlling for one or more demographic and known biomedical prognostic factors.