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Table 4 Studies on relationship between quality of life data and survival in patients with gastro-oesophageal cancers

From: Quality of life data as prognostic indicators of survival in cancer patients: an overview of the literature from 1982 to 2008

Author(s) Year Sample HRQOL measure(s) Results*
Blazeby et al. [64] 2000 89 oesophageal cancer EORTC QLQ-C30 + Dysphagia scale of QLQ-OES24 Physical functioning at baseline was significantly associated with survival.
Blazeby et al. [65] 2001 89 oesophageal cancer EORTC QLQ-C30 + Dysphagia scale of QLQ-OES24 Physical functioning at baseline was significantly associated with survival. After treatment, improved emotional functioning was significantly related to longer survival.
Fang et al. [66] 2004 110 oesophageal squamous cell cancer EORTC QLQ-C30 Pretreatment physical functioning was the most significant survival predictor while QOL scores during treatment were not. After treatment dysphagia was the most significant predictor.
Chau et al. [67] 2004 1080 locally advanced or metastatic oesophago-gastric cancer EORTC QLQ-C30 Pretreatment physical and role functioning and global QOL predicted survival.
Park et al. [68] 2008 164 advanced gastric cancer EORTC QLQ-C30 Social functioning was significant prognostic factor for survival.
Bergquist et al. [69] 2008 96 advanced oesophageal cancer EORTC QLQ-C30 + QLQ-OES18 Physical functioning, fatigue and reflux were significant prognostic of survival.
McKernan et al. [70] 2008 152 gastric or oesophageal cancer EORTC QLQ-C30 Appetite loss was significantly independent predictor of survival.
Healy et al. [71] 2008 185 localized oesophageal cancer EORTC QLQ-C30 Fatigue score was predictive of 1-year survival but global QOL data were not.
  1. Abbreviations: EORTC QLQ-C30: European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire; QLQ-OES18 (previously QLQ-OES24): EORTC Oesophageal Cancer specific Quality of Life Questionnaire; QOL: quality of life.
  2. * All results obtained from multivariate analyses after controlling for one or more demographic and known biomedical prognostic factors.