Table 4 Studies on relationship between quality of life data and survival in patients with gastro-oesophageal cancers
Author(s) | Year | Sample | HRQOL measure(s) | Results* |
|---|---|---|---|---|
Blazeby et al. [64] | 2000 | 89 oesophageal cancer | EORTC QLQ-C30 + Dysphagia scale of QLQ-OES24 | Physical functioning at baseline was significantly associated with survival. |
Blazeby et al. [65] | 2001 | 89 oesophageal cancer | EORTC QLQ-C30 + Dysphagia scale of QLQ-OES24 | Physical functioning at baseline was significantly associated with survival. After treatment, improved emotional functioning was significantly related to longer survival. |
Fang et al. [66] | 2004 | 110 oesophageal squamous cell cancer | EORTC QLQ-C30 | Pretreatment physical functioning was the most significant survival predictor while QOL scores during treatment were not. After treatment dysphagia was the most significant predictor. |
Chau et al. [67] | 2004 | 1080 locally advanced or metastatic oesophago-gastric cancer | EORTC QLQ-C30 | Pretreatment physical and role functioning and global QOL predicted survival. |
Park et al. [68] | 2008 | 164 advanced gastric cancer | EORTC QLQ-C30 | Social functioning was significant prognostic factor for survival. |
Bergquist et al. [69] | 2008 | 96 advanced oesophageal cancer | EORTC QLQ-C30 + QLQ-OES18 | Physical functioning, fatigue and reflux were significant prognostic of survival. |
McKernan et al. [70] | 2008 | 152 gastric or oesophageal cancer | EORTC QLQ-C30 | Appetite loss was significantly independent predictor of survival. |
Healy et al. [71] | 2008 | 185 localized oesophageal cancer | EORTC QLQ-C30 | Fatigue score was predictive of 1-year survival but global QOL data were not. |