Table 3 ANCOVAs comparing VFQ-25 change scores among groups of patients differing in visual acuity change from baseline to month 18â€
Change in VFQ-25 score mean (SD) | Improved by ≥ 10 (N = 32–35) | Improved by 5 to 9 (N = 80–85) | No change (-4 to +4) (N = 300–323) | Worsened by 5 to 9 (N = 47–53) | Worsened by ≥ 10 (N = 36–39) | Overall F value | Change in best visual acuity p-value | Significant pairwise comparisons |
|---|---|---|---|---|---|---|---|---|
General vision | 9.1 (17.0) | 3.3 (16.9) | -0.2 (15.8) | -1.5 (14.1) | -13.3 (19.1) | 5.98*** | <0.0001 | D***, G***, I***, J* |
Ocular pain | 1.8 (15.2) | -0.1 (16.3) | 2.2 (14.8) | 2.4 (13.9) | 1.6 (15.0) | 0.68 | 0.74 | Â |
Near vision | 6.3 (17.7) | 3.6 (17.9) | 1.1 (17.2) | -4.5 (16.1) | -15.8 (24.9) | 6.16*** | <0.0001 | D***, G***, I*** |
Distance vision | 2.7 (12.8) | 1.4 (14.8) | 0.3 (14.3) | -5.6 (14.9) | -16.2 (19.5) | 8.45*** | <0.0001 | D***, G***, I***, J* |
Social function | 2.9 (7.5) | -0.9 (9.9) | -0.5 (10.6) | -3.3 (14.3) | -11.2 (24.1) | 5.24*** | <0.0001 | D***, G***, I*** |
Mental health | 7.3 (17.9) | 2.3 (15.1) | 0.5 (16.9) | -3.3 (22.9) | -17.5 (28.1) | 6.39*** | <0.0001 | D***, G***, I***, J* |
Role limitations | 3.6 (15.6) | 3.8 (21.0) | 0.2 (17.9) | -6.4 (23.6) | -21.5 (31.4) | 7.59*** | <0.0001 | D***, G***, I***, J* |
Dependency | 3.3 (14.0) | -3.0 (13.8) | -0.3 (14.3) | -7.5 (22.8) | -26.1 (32.8) | 13.35*** | <0.0001 | C*, D***, G***, I***, J*** |
Driving | 0.1 (18.9) | -2.1 (14.1) | -1.8 (15.4) | -6.9 (19.1) | -22.9 (35.1) | 7.91*** | <0.0001 | D***, G***, I***, J** |
Color vision | 2.3 (15.8) | -1.5 (14.7) | 0.6 (12.4) | -3.8 (17.4) | -11.5 (31.3) | 3.56*** | 0.0001 | D*, G*, I*** |
Peripheral vision | 5.7 (20.2) | -2.6 (17.3) | -0.5 (18.6) | -5.0 (22.0) | -16.7 (32.1) | 4.52*** | <0.0001 | D***, G*, I*** |
Overall VFQ-25 score | 3.9 (9.1) | 0.2 (10.1) | 0.1 (8.9) | -4.4 (11.4) | -15.6 (19.2) | 13.99*** | <0.0001 | C**, D***, G***, I***, J*** |