Table 4 GSRS and GIQLI scores by physician's rating of clinical disease severity at baseline
Groups by rating of clinical severity | Kruskall-Wallis Test of overall differences | ||||||
|---|---|---|---|---|---|---|---|
Patient reported outcome instrument and domain | None (n = 20) mean (SD) | Mild (n = 6) mean (SD) | Moderate (n = 32) mean (SD) | Severe (n = 4) mean (SD) | Chi-Square | p-value | Wilcoxon rank-sum tests (pairwise comparisons with p < 0.001) |
GSRS Abdominal Pain | 1.33 (0.42) | 2.61 (0.93) | 3.29 (1.23) | 3.83 (1.69) | 33.75 | <0.001 | b |
GSRS Reflux Syndrome | 1.10 (0.26) | 2.42 (1.32) | 3.09 (1.46) | 4.00 (2.12) | 29.25 | <0.001 | b, c |
GSRS Diarrhea | 1.12 (0.20) | 3.61 (1.69) | 3.57 (1.56) | 2.67 (1.70) | 37.21 | <0.001 | a, b |
GSRS Indigestion Syndrome | 1.29 (0.33) | 3.29 (1.81) | 3.76 (1.43) | 4.81 (1.68) | 38.29 | <0.001 | a, b |
GSRS Constipation | 1.20 (0.38) | 1.94 (0.65) | 2.55 (1.26) | 3.42 (2.23) | 27.03 | <0.001 | b |
GIQLI Total Score | 126.00 (10.97) | 95.83 (23.22) | 87.02 (22.08) | 65.00 (37.37) | 33.25 | <0.001 | b |
GIQLI Symptoms | 3.64 (0.30) | 2.65 (0.68) | 2.49 (0.57) | 1.87 (0.82) | 35.31 | <0.001 | b |
GIQLI Emotion | 3.24 (0.64) | 2.87 (0.70) | 2.47 (0.74) | 1.60 (0.86) | 16.33 | <0.001 | |
GIQLI Physical Function | 3.21 (0.61) | 2.14 (0.89) | 1.92 (0.91) | 1.61 (1.62) | 22.00 | <0.001 | b |
GIQLI Social Function | 3.55 (0.60) | 3.04 (0.70) | 2.74 (0.96) | 2.19 (1.60) | 10.22 | 0.017 | |
GIQLI Medical Treatment | 3.95 (0.22) | 4.00 (0.00) | 2.94 (1.11) | 1.50 (1.91) | 21.25 | <0.001 | b, c |