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Table 3 Responsiveness indicators for all patients by esomeprazole and placebo treatment

From: The Reflux Disease Questionnaire: a measure for assessment of treatment response in clinical trials

RDQ Scale Effect size Standardized response mean
  Esomeprazole Placebo Esomeprazole Placebo
Heartburn 2.05 0.85 1.52 0.74
Regurgitation 1.36 0.63 1.31 0.60
Dyspepsia 1.05 0.56 0.99 0.57
GERDa 2.13 0.93 1.68 0.79
  1. aHeartburn and regurgitation subscales combined.