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Table 2 PedsQL™ 3.0 acute cancer module Parent Form

From: Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study

 

T1 (n = 15)

T2 (n = 37)

 

Dexa + Mean (SD)

Dexa – Mean (SD)

Effect size1

p2

Dexa + Mean (SD)

Dexa – Mean (SD)

Effect size1

p3

Total

68.0 (15.6)

77.0 (8.5)

-0.58

0.01

66.2 (14.6)

73.1 (13.1)

-0.47

<0.01

Pain

53.3 (21.9)

72.6 (15.1)

-0.88

0.02

41.9* (26.2)

65.9 (21.8)

-0.91

<0.01

Nausea

74.5 (21.7)

75.0 (17.3)

0.02

NS

73.9 (22.4)

67.0 (22.1)

0.30

0.04

Procedural Anxiety

55.6 (33.7)

63.3 (27.4)

-0.23

0.03

71.2(29.3)

75.5 (24.2)

-0.15

NS

Treatment Anxiety

75.0 (30.7)

83.3 (25.0)

-0.27

0.04

80.6 (22.8)

84.5 (22.4)

-0.17

NS

Worry

86.1 (23.5)

87.2 (15.1)

-0.05

NS

69.4 (29.7)

76.4 (24.9)

-0.24

NS

Cognitive

66.2 (27.5)

80.8 (17.4)

-0.53

NS

54.6* (23.2)

72.8 (19.7)

-0.78

<0.01

Physical appearance

65.6 (28.3)

77.8 (19.3)

-0.43

0.03

62.1 (27.6)

69.3* (24.9)

-0.26

<0.01

Communication

62.0 (39.3)

75.1 (28.7)

-0.33

0.03

67.1 (28.5)

75.6 (24.2)

-0.30

<0.01

  1. Higher scores indicate a better QoL
  2. 1 Effect size = negative effect size indicates worse QoL in the group on dexamethasone. Positive effect size indicates better QoL in the group on dexamethasone: 0.2 ≤ d < 0.5 = small effect; 0.5 ≤ d < 0.8 = moderate effect; d ≥ 0.8 = large effect.
  3. 2 Dexa + versus Dexa - at T1, Wilcoxon signed ranks test
  4. 3 Dexa + versus Dexa - at T2, T-test for paired samples
  5. * significant difference T1 vs. T2