| Mild/Moderate Fatigue (N = 2386) | Severe Fatigue (N = 6691) | P value |
---|---|---|---|
Demographic Characteristics | Â | Â | Â |
Mean age, years (± sd) | 45.8 (± 11) | 48.3 (± 10) | <.0001 |
Gender: female, % | 75.8 | 70.6 | <.0001 |
Race: Caucasian, % | 92.6 | 92.9 | Â |
Education: associate or less, % | 52.0 | 61.5 | <.0001 |
Employed, % | 54.6 | 29.0 | <.0001 |
MS Characteristics | Â | Â | Â |
Mean age at diagnosis, years (± sd) | 36.5 (± 9.6) | 38.0 (± 9.6) | <.0001 |
MS duration (years since diagnosis) (± sd) | 12.1 (± 9.5) | 13.1 (± 9.6) |  |
Disability: mean PDDS score | 2.58 | 4.22 | <.0001 |
MS types, % | Â | Â | <.0001 |
   Relapsing-stable | 59.6 | 32.6 |  |
   Relapsing-worsening | 26.5 | 59.8 |  |
   Primary progressive | 14.0 | 7.6 |  |
Treatment with symptomatic drugs for fatigue, % | 18.2 | 46.5 | Â |