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Table 5 Properties of validity for diagnosis of pain with neuropathic involvement in different subgroups by pain severity and educational level in the overall sample.

From: Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component

Cut-off value ≥ 4 points Sensitivity (%) Specificity (%) PPV (%) NPV (%) Kappa
Pain severity (VAS)      
Mild; < 40 mm (n = 12) 55.6 66.7 83.3 33.3 0.17
Moderate; ≥ 40 and < 70 mm (n = 65) 85.0 84.0 89.5 77.8 0.68†††
Severe; ≥ 70 mm (n = 81) 80.0 74.2 83.3 69.7 0.54†††
Educational level      
No studies (n = 39) 81.3 73.9 68.4 85.0 0.54††
Primary school (n = 69) 77.1 81.0 90.2 60.7 0.53†††
High school (n = 14) 83.3 100 100 50.0 0.59
Vocational training (n = 16) 78.6 100.0 100 40 0.48
Graduate studies (n = 18) 87.5 70.0 70.0 87.5 0.56
  1. VAS = Visual Analogue Scale for pain (0 – 100 mm) of McGill short pain questionnaire, PPV = Positive Predictive Value, NPV = Negative Predictive Value. p > 0.05; p < 0.05; ††p < 0.01; †††p < 0.001. Two patients did not report their educational level.