Validation of two generic patient-reported outcome measures in patients with type 2 diabetes

Table 7 Known-groups validity of the EQ-5D and PGWB Global Score: Comparisons between groups of patients

Variable Used to Differentiate Groups	Groups	EQ-5D Index Score		EQ-5D VAS		PGWB Global Score
		Mean	t Value	Mean	t Value	Mean	t Value
ADS Median Split	ADS Score ≤ 16 (n = 58)	0.88	5.1***	76.7	5.0***	78.9	7.3***
	ADS Score > 16 (n = 72)	0.65		62.5		59.0
DSC-R Median Split	DSC-R Total Score ≤ 0.7 (n = 61)	0.91	6.6***	78.8	7.0***	79.6	8.2***
	DSC-R Total Score > 0.7 (n = 69)	0.61		60.0		57.5
Preference for Weight Change	Lose weight (n = 113)	0.73	-4.4***	66.7	-5.0***	66.5	-2.0*
	Stay same (n = 16)	0.92		83.0		76.9
Experienced Hypoglycemia During the Day	Yes (n = 53)	0.68	-2.6*	62.6	-3.4***	64.0	-2.3*
	No (n = 74)	0.82		73.9		71.8
Experienced Hypoglycemia During the Night	Yes (n = 23)	0.60	-3.2**	64.2	-1.5	58.8	-3.0**
	No (n = 101)	0.80		70.6		71.0
Experienced Hyperglycemia	Yes (n = 64)	0.73	-1.1	64.5	-2.8**	64.9	-2.1*
	No (n = 63)	0.78		73.4		71.6
Type of Treatment	Injectable (n = 31)	0.65	-1.8	61.4	-2.0	62.6	-1.3
	Oral only (n = 85)	0.78		70.2		68.9

ADS = Appraisal of Diabetes Scale; DSC-R = Diabetes Symptom Checklist – Revised; PGWB = Psychological General Well-Being Index; VAS = Visual Analog Scale; *p < 0.05; **p < 0.01; ***p < 0.001

ISSN: 1477-7525