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Table 5 Parent Proxy-Report: Means and Standard Deviations for the PedsQL™ 4.0 Generic Core Scales by Disease Category.

From: Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL™ 4.0 Generic Core Scales

  

Total Score

Physical Health

Psychosocial Health

Emotional Functioning

Social Functioning

School Functioning

 

n

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

Asthma

       

Mild Intermittenta

206

86.90 (13.23)

88.80 (14.37)

85.86 (15.63)

85.60 (17.84)

88.43 (17.26)

83.02 (20.97)

Mild Persistentb

68

76.77 (16.23)

76.15 (21.40)

77.11 (16.74)

74.54 (20.58)

82.23 (18.71)

75.00 (22.76)

Moderate to Severe Persistent c

63

69.88 (16.82)

64.76 (21.93)

72.65 (18.10)

69.84 (22.30)

76.85 (24.80)

71.39 (23.34)

Differences

 

a > b, c***; b > c*

a > b, c***; b > c**

a > b, c***

a > b, c***

a > c***

a > b*; a > c**

Cancer

       

Acute Lymphoblastic Leukemiaa

170

71.29 (18.11)

71.20 (22.54)

71.35 (17.90)

67.57 (19.97)

77.00 (20.40)

68.03 (22.51)

Brain Tumor b

249

66.21 (19.22)

65.17 (25.24)

67.01 (18.89)

67.34 (21.11)

68.43 (23.92)

65.12 (23.53)

Newly Diagnosed On-Treatment¤

180

66.95 (19.85)

65.00 (26.26)

68.19 (18.25)

63.26 (20.70)

75.58 (20.08)

63.61 (24.03)

Long-Term Survivor Off-Treatment > 12 months§

94

73.64 (18.72)

74.80 (24.08)

72.95 (18.07)

72.93 (19.94)

76.28 (21.71)

68.87 (23.08)

Differences

 

a > b**;§ > ¤**

a > b*; § > ¤**

a > b*; § > ¤*

§ > ¤***

a > b***

_____

Cardiac

       

Disease Severity Group 1 a

82

88.06 (12.04)

93.03 (10.39)

84.98 (14.63)

81.05 (19.23)

91.38 (14.19)

80.86 (17.88)

Disease Severity Group 2 b

143

80.50 (15.13)

84.32 (18.39)

78.28 (15.58)

75.78 (20.12)

84.55 (18.73)

72.68 (19.54)

Disease Severity Group 3 c

93

78.62 (16.21)

81.86 (18.63)

76.92 (17.57)

74.50 (20.97)

81.66 (20.40)

72.46 (20.36)

Disease Severity Group 4 d

108

73.42 (18.11)

75.37 (21.35)

72.41 (18.49)

70.10 (21.29)

76.17 (22.09)

68.68 (23.22)

Differences

 

a > b**; a > c, d***; b > d**

b > d**; a > b**; a > c, d***

a > b*; a > c**; a > d***; b > d*

a > d**

a > c**; b > d**; a > d***

a > b*; a > d**

Cerebral Palsy

       

Hemiplegiaa

49

57.67 (20.00)

55.72 (25.78)

58.94 (19.45)

62.19 (21.71)

55.92 (24.02)

57.26 (22.56)

Diplegiab

67

54.03 (15.87)

47.02 (22.15)

58.01 (15.97)

63.31 (19.32)

53.88 (20.29)

56.39 (20.40)

Paraplegiac

73

44.78 (15.30)

31.88 (27.19)

52.00 (14.80)

61.31 (17.61)

48.29 (20.62)

45.24 (19.65)

Differences

 

a > c***; b > c**

a > c***; b > c**

_____

_____

_____

a, b > c**

Diabetes

       

Type 1 a

226

77.31 (14.12)

82.38 (17.82)

74.53 (15.17)

69.11 (18.64)

82.33 (18.78)

71.87 (19.11)

Type 2 b

78

74.71 (14.01)

81.06 (15.64)

71.28 (15.77)

69.47 (18.26)

77.21 (20.70)

67.42 (20.14)

Differences

 

_____

_____

_____

_____

a > b*

_____

End Stage Renal Disease

       

Transplanta

45

75.57 (17.75)

78.38 (24.65)

74.14 (17.50)

75.67 (18.36)

78.56 (22.20)

66.06 (18.53)

Peritoneal Dialysisb

19

68.07 (15.02)

68.40 (20.01)

67.97 (14.79)

62.11 (17.90)

73.42 (17.95)

69.30 (16.21)

Hemodialysisc

31

61.94 (17.70)

62.52 (23.45)

61.69 (17.23)

62.74 (19.79)

66.13 (19.27)

56.21 (25.62)

Differences

 

a > c**

a > c*

a > c**

a > b, c*

a > c*

_____

Gastrointestinal Conditions

       

Irritable Bowel Syndromea

122

74.82 (14.27)

78.68 (15.83)

72.72 (15.30)

66.19 (19.61)

82.54 (17.34)

69.35 (20.48)

Functional Abdominal Painb

82

73.65 (12.23)

77.70 (15.41)

71.49 (12.87)

65.49 (16.59)

79.94 (15.20)

68.93 (17.99)

Organic Disordersc

82

68.75 (16.97)

70.31 (18.82)

67.95 (18.03)

63.41 (21.30)

77.33 (21.29)

63.13 (20.96)

Differences

 

a > c*

a > c*

_____

_____

_____

_____

Obesity

       

Severely Obesea

105

63.30 (19.20)

63.60 (24.00)

63.10 (18.60)

60.90 (21.70)

67.20 (26.10)

61.40 (21.50)

Obeseb

63

75.00 (14.50)

76.30 (17.60)

73.90 (15.30)

72.60 (17.80)

73.50 (17.30)

76.60 (17.00)

Overweightc

294

80.00 (13.60)

82.60 (17.20)

76.10 (14.40)

74.90 (15.80)

82.30 (16.10)

78.40 (17.10)

Differences

 

b, c > a***; c > b**

c > b**; c > a***; b > a**

b, c > a***

c > a***; b > a**

c > a***; c > b**

b, c > a***

Psychiatric Disorders

       

Attention-Deficit and Disruptive Behavior Disordersa

107

65.80 (13.50)

80.30 (16.20)

58.00 (15.40)

54.90 (18.70)

59.10 (22.50)

59.80 (17.80)

Anxiety Disordersb

57

66.00 (14.20)

80.30 (17.60)

58.20 (15.10)

46.80 (16.70)

66.30 (25.70)

62.00 (17.80)

Mood Disorders c

29

65.70 (11.70)

79.20 (17.80)

58.60 (12.30)

49.10 (16.90)

66.20 (18.40)

60.60 (16.70)

Pervasive Developmental Disorders d

28

61.50 (13.10)

76.30 (22.00)

53.70 (12.40)

53.70 (14.00)

47.20 (20.20)

61.40 (15.80)

Differences

 

_____

_____

_____

a > b**

_____

_____

Rheumatology

       

Systemic Lupus Erythematosusa

18

75.25 (17.69)

70.16 (25.35)

78.00 (15.67)

72.50 (21.71)

83.61 (16.79)

78.53 (17.30)

Spondyloarthritisb

33

73.63 (18.20)

70.08 (27.65)

75.49 (15.31)

75.00 (17.94)

81.09 (19.17)

70.61 (18.91)

Juvenile Rheumatoid Arthritisc

124

73.48 (18.95)

70.07 (24.07)

75.36 (18.13)

74.58 (19.89)

76.73 (20.89)

74.66 (22.50)

Fibromyalgiad

57

52.07 (15.17)

43.37 (19.01)

56.70 (16.41)

48.95 (19.47)

67.02 (19.70)

53.77 (20.55)

Differences

 

a, b, c > d***

a, b, c > d***

a, b, c > d***

a, b, c > d***

a, b, c > d*

a, b > d**; c > d***

  1. Note: *p < .05, **p < .01, ***p < .001 based on Tukey post-hoc analysis when more than 2 disease categories are being compared and independent samples t-test when 2 disease categories are being compared. Contrasts for cancer disease categories are for Acute Lymphoblastic Leukemiaa versus Brain Tumorband Newly Diagnosed On-Treatment ¤ versus Long Term Survivor Off-Treatment > 12 months §. Asthma contrasts are based on the PedsQL™ 4.0 SF15, a shorted version of the 23-item PedsQL™ 4.0 Generic Core Scales.