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Table 1 Algorithms to convert item responses from generic health-related quality of life instruments into utility measures

From: Which health-related quality of life score? A comparison of alternative utility measures in patients with Type 2 diabetes in the ADVANCE trial

Study (denoted by primary author and instrument)

Dolan EQ-5D

Shaw EQ-5D

Brazier SF-6D (SF-12)

Brazier SF-6D (SF-36)

Lundberg SF-12

Lawrence SF-12 (MEPS)

Franks SF-12 (MEPS)

Franks SF-12

Fryback SF-36

Type of Algorithm

EQ-5D based algorithm

SF-6D based algorithm

SF-12 based algorithm

SF-36 based algorithm

QoL Questionnaire

EQ-5D

EQ-5D

SF-12

SF-36

SF-12

SF-12

SF-12

SF-12

SF-36

Number items used

5

5

7

11 (of 36)

12 (of 36)

12

12

12

36

Methods for valuing utility

Time Trade Off

Time Trade Off

Standard Gamble

Standard Gamble

Time Trade Off

Mapping to the UK based EQ-5D tariffs

Mapping to the UK based EQ-5D tariffs

Mapping to the UK based EQ-5D tariffs

Quality well being index

Reported range in the ADVANCE trial patients

-0.18 to 1

0.20 to 1

0.41 to 1

0.35 to 1

0.47 to 0.98

0.20 to 1.01

0.046 to 0.975

-0.07 to 0.94

0.509 to 0.836

Health states sampled

243

243

249

249

NA

NA

NA

NA

NA

Population

General population

General population

General population

General population

General population

General population

General population

Low income, minority population

General population

Country where developed

UK

USA

UK

UK

Sweden

USA

USA

USA

USA

Description of process

3,667 individuals rating 12 health states from the possible 243 states.

4,048 individuals rating 13 from the possible 243 states.

611 individuals rating 6 health states from 6-dimensional health state classification (3518 observations)

611 individuals rating 6 health states from 6-dimensional health state classification (3518 observations)

Postal questionnaire 5,400 individuals using SF12 plus TTO question. Regression used to derive utilities.

14,580 respondents who completed the Medical Expenditure Panel survey 2000.

15,000 respondents who completed the Medical Expenditure Panel survey 2000.

240 respondents attending a community health centre in New York

1,356 respondents who participated in the Beaver Dam Health study