Patient-reported outcomes in a trial of exenatide and insulin glargine for the treatment of type 2 diabetes

Table 3 Change in health outcomes associated with exenatide and insulin glargine

Health Outcomes Measure	Exenatide			Insulin Glargine
	N	LS Mean	SE	N	LS Mean	SE	p value¹
DSC-R Overall Score	223	-0.16	0.04	219	-0.16	0.05	0.96
EQ-5D Index Score	217	0.02	0.01	215	0.03	0.01	0.35
Diabetes Treatment Flexibility Score	222	0.32	1.28	219	-0.46	1.27	0.59
Diabetes Treatment Satisfaction Score	213	3.42	0.43	213	3.85	0.43	0.38
SF-36 Vitality Subscale Score	223	2.41	1.24	220	2.81	1.25	0.78
DSC-R Psychology: Fatigue Score	222	-0.28	0.08	220	-0.31	0.08	0.73
DSC-R Psychology: Cognitive Score	223	-0.24	0.06	220	-0.29	0.06	0.52
DSC-R Neurology: Pain Score	222	-0.04	0.06	219	-0.03	0.06	0.93
DSC-R Neurology: Sensory Score	223	-0.03	0.06	219	0.02	0.06	0.45
DSC-R Cardiology Score	223	-0.08	0.06	219	-0.14	0.06	0.30
DSC-R Ophthalmology Score	222	-0.19	0.06	219	-0.16	0.06	0.68
DSC-R Hypoglycemia Score	221	-0.20	0.07	219	-0.22	0.07	0.81
DSC-R Hyperglycemia Score	223	-0.35	0.07	220	-0.39	0.07	0.58
DTSQ Frequency High Blood Sugar	219	-1.40	0.12	218	-1.48	0.12	0.58
DTSQ Frequency Low Blood Sugar	218	0.37	0.12	216	0.58	0.12	0.13

¹Comparisons between treatment groups were performed with general linear models. One model was conducted with each health outcomes measure as the dependent variable, controlling for country and baseline score.

ISSN: 1477-7525