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Table 5 Change in SF-36 norm based Domain scores in refractory HCV patients re-treated with pegylated interferon alpha 2b and ribavirin: Responders versus non-responders

From: Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin

SF-36 domain

Change from baseline at (responders minus non-responders)

 

24 wks

48 wks

72 wks

Physical Function

-3.26

-0.65

-0.32

Role-Physical

-2.68

0.62

5.26

Bodily Pain

0.42

2.02

0.64

General Health

-3.35

-0.85

2.91

Vitality

-4.82

-3.89

3.64

Social Functioning

-3.91

0.71

5.09

Role-Emotional

-2.98

2.00

6.12

Mental Health

-2.47

0.92

-0.48

Physical Component Score

-2.65

-0.71

1.18

Mental Component Score

-3.06

0.30

2.30

  1. None of the changes were statistically significant. Negative value suggest a worse score in responders