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Table 3 Change in SF-36 norm based Domain scores in responders among refractory HCV patients re-treated with pegylated interferon alpha 2b and ribavirin

From: Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin

SF-36 domain

Change in QOL scores compared to baseline At

48 wks to 24 wks (24 wk-48 wk)

 

24 wks

48 wks

72 wks

 

Physical Function

-5.25*

-2.02

1.04

3.23

Role Physical

-7.02

-4.87

5.15

2.14

Bodily Pain

-3.31

-2.13

1.96

1.18

General Health

-4.53*

-3.88

1.55

0.65

Vitality

-8.28**

-8.40^

5.69

-0.12

Social Functioning

-7.33

-5.30

4.87

2.03

Role-Emotional

-4.98

-2.42

5.50

2.56

Mental Health

-4.32

-3.76

0.10

0.56

Physical Component Score

-5.99^^

-3.54

2.26

2.45

Mental Component Score

-5.20*

-3.48

2.49

1.71

  1. *p = .01 to .05, ** p = .001, ^ p = .003, ^^ p = .007. Negative value suggests a decrease in the QOL domain