Parsimonious and efficient assessment of health-related quality of life in osteoarthritis research: validation of the Assessment of Quality of Life (AQoL) instrument

Whitfield, Kathryn; Buchbinder, Rachelle; Segal, Leonie; Osborne, Richard H

doi:10.1186/1477-7525-4-19

Table 3 Ability of the instruments to discriminate between OWL patients and community group

From: Parsimonious and efficient assessment of health-related quality of life in osteoarthritis research: validation of the Assessment of Quality of Life (AQoL) instrument

	Waiting List v Community				Comparison of Means				ROC			Absolute Performance Gain
Instruments	Community (n = 111)		OWL (n = 45)		Effect size #	SD.	t	RE	Area Under Curve	Asymptotic 95% CI		Z	APG %	95% CI
	M	SD.	M	SD						Lower	Upper			Lower	Upper
AQOL
Utility Score	0.50	0.19	0.37	0.25	0.66	0.21	3.7**	1.00	**0.67	0.57	0.77	reference
Independent living	0.80	0.18	0.69	0.22	0.58	0.19	3.3**	0.79	*0.66	0.57	0.75	0.10	1.9	-16.6	20.5
Social relationships	0.84	0.15	0.76	0.26	0.24	0.19	2.4*	0.41	0.56	0.45	0.67	1.08	21.5	1.9	41.1
Physical senses	0.90	0.09	0.92	0.07	-0.26	0.08	-1.4	0.16	0.43	0.33	0.53	^1.97	48.5	24.4	72.7
Psychological wellbeing	0.81	0.11	0.67	0.23	0.88	0.15	4.9**	1.78	*0.65	0.54	0.76	0.22	4.4	-15.2	23.9
SF-36
Physical function	40.8	21.0	29.8	24.9	0.50	22.2	2.8*	0.57	**0.67	0.57	0.77	-0.02	0.5	-22.7	23.8
Role physical	26.7	37.1	10.6	22.9	0.48	33.7	2.7*	0.53	*0.61	0.52	0.70	0.47	11.6	-12.3	35.5
Bodily pain	42.7	18.8	33.9	17.2	0.48	18.3	2.7*	0.53	*0.63	0.53	0.72	0.43	8.8	-11.1	28.7
General health	56.6	22.2	51.7	20.8	0.22	21.8	1.3	0.12	0.56	0.47	0.66	0.86	21.1	-3.0	45.2
Vitality	44.7	19.5	43.3	22.0	0.07	20.2	0.4	0.01	0.52	0.42	0.63	1.22	29.4	5.8	53.1
Social function	68.4	24.8	56.4	28.7	0.46	26.0	2.6*	0.49	*0.62	0.52	0.72	0.46	9.8	-11.2	30.9
Role emotional	55.1	44.6	43.0	45.9	0.27	45.0	1.5	0.17	0.57	0.47	0.67	0.81	19.9	-4.2	44.0
Mental health	68.3	17.9	61.3	22.3	0.36	19.2	2.1*	0.30	0.59	0.48	0.69	0.69	16.5	-6.9	39.8
PCS	31.8	9.3	27.8	8.1	0.44	9.0	2.5*	0.46	*0.64	0.55	0.74	0.20	5.0	-19.5	29.4
MCS	47.8	11.6	44.9	13.4	0.24	12.1	1.4	0.13	0.56	0.46	0.66	0.91	21.4	-1.6	44.3
WOMAC
Pain	41.6	20.7	54.3	21.9	-0.60	21.0	-3.4**	0.84	*0.66	0.57	0.76	0.08	1.7	-20.3	0.2
Stiffness	50.0	18.5	59.4	18.9	-0.51	18.6	-2.9*	0.60	*0.63	0.53	0.72	0.37	8.3	-13.5	0.3
Physical function	42.5	19.4	58.5	19.3	-0.82	19.4	-4.7**	1.57	**0.71	0.62	0.80	-0.38	8.1	-12.8	0.3
Total score	42.9	18.4	57.7	19.0	-0.79	18.6	-4.5**	1.46	**0.70	0.61	0.79	-0.28	6.0	-14.7	0.3
VAS (over past week)
Average pain	-43.7	23.8	-60.7	21.6	0.74	23.2	4.2**	1.26	**0.70	0.61	0.79	-0.28	6.0	-0.2	0.3
Pain at rest	-26.9	22.2	-41.8	22.6	0.67	22.3	3.8**	1.03	**0.70	0.61	0.78	-0.22	5.0	-0.2	0.3
ADL Restriction	-37.8	26.0	-51.2	23.9	0.53	25.4	3.0*	0.64	*0.65	0.56	0.74	0.18	3.9	-0.2	0.3

^# Note: For the effect size calculations the Community group was nominated as the 'control group'. * p < 0.05, ** p < 0.001, ^ p > 0.05.

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ISSN: 1477-7525

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