The effect of patient characteristics on variability in pain and function over two years in early knee osteoarthritis

Table 1 The effect of demographic characteristics on clinically relevant variation in pain over two years*

	KOOS Pain					SF-36 Bodily Pain
Characteristic	Prevalence of clinically relevant change		Unadjusted for baseline values	Adjusted for baseline values		Prevalence of clinically relevant change		Unadjusted for baseline values	Adjusted for baseline value
	N	%	OR	OR	95% CI	N	%	OR	OR	95% CI
Age
<46†	11/49	22				27/49	55
46–56	17/47	36	1.5	1.1	0.4–3.1	32/47	68	1.2	1.1	0.4–2.8
>56	12/47	26	1.0	0.9	0.3–2.4	34/47	72	1.9	1.7	0.7–4.5
Gender
men†	35/120	29				78/120	65
women	5/23	22	1.2	0.5	0.2–1.8	15/23	65	1.2	1.1	0.4–3.2
BMI (kg/m²)
<25†	10/61	16				34/61	56
25–29.9	22/64	34	2.4	2.0	0.8–4.9	47/64	73	2.3	1.9	0.8–4.3
≥30	7/16	44	4.0	1.8	0.4–7.1	11/16	69	1.4	0.6	0.2–2.5

KOOS = Knee injury and Osteoarthritis Outcome Score, OR = odds ratio, 95% CI = 95% confidence interval, BMI = body mass index.
* All risk factors listed are entered simultaneously in each model.
† Reference category.

ISSN: 1477-7525